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Primary anal adenocarcinoma: a caution for conservative treatment

Published online by Cambridge University Press:  30 November 2006

J. Martin ,
S. Y. K. Ngan  and
T. Leong
J. Martin
Affiliation:
Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
S. Y. K. Ngan
Affiliation:
Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia
T. Leong
Affiliation:
Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia
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Abstract

There is evidence that a conservative approach with chemoradiotherapy can achieve long-term local control in patients with anal adenocarcinoma. Identification of suitable patients for this approach remains a problem. We describe a patient with a clinically staged T2N0 tumour, who achieved a complete clinical response on magnetic resonance imaging and positron emission tomography after chemoradiotherapy, but was noted to have residual disease with evidence of lymph node metastasis on pathological examination in the abdominoperineal resection specimen. A complete clinical response does not necessarily equate to pathological response.

Keywords

Anal tumoursadenocarcinomaradiotherapychemotherapysurgery
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 5 , Issue 4 , December 2006 , pp. 233 - 236
Copyright
2006 Cambridge University Press

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