Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-11T02:53:52.933Z Has data issue: false hasContentIssue false

Primary mucosa-associated lymphoid tissue lymphoma of the thyroid with concomitant papillary carcinoma

Published online by Cambridge University Press:  20 February 2014

Shaakir Hasan
Affiliation:
College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA
Aruna Turaka*
Affiliation:
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
*
Correspondence to: Aruna Turaka, Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Tel: 215 728 3022. Fax: 215 214 1629. E-mail: aruna.turaka@fccc.edu

Abstract

Objective

Papillary thyroid carcinoma combined with thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare and there is no standard management.

Case report

We report a rare association of MALT lymphoma of thyroid in a 60-year-old woman with Hashimoto's thyroiditis along with an incidental focus of papillary carcinoma.

Conclusion

Patients with Hashimoto's thyroiditis are prone to develop other thyroid pathology, including rare tumours such as MALT lymphoma. The differential diagnosis for a neoplasm in such patients should be wide.

Type
Case Study
Copyright
Copyright © Cambridge University Press 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Derringer, G A, Thompson, L D, Frommelt, R A, Bijwaard, K E, Heffess, C S, Abbondanzo, S L. Malignant lymphoma of the thyroid gland: a clinicopathologic study of 108 cases. Am J Surg Pathol 2000; 24: 623639.Google Scholar
2. Earnest, L M, Cooper, D S, Sciubba, J J, Tufano, R P. Thyroid MALT lymphoma in patients with a compressive goiter. Head Neck 2006; 28: 765770.CrossRefGoogle ScholarPubMed
3. Blair, T J, Evans, R G, Buskirk, S J, Banks, P M, Earle, J D. Radiotherapeutic management of primary thyroid lymphoma. Int J Radiat Oncol Biol Phys 1985; 11: 365370.CrossRefGoogle ScholarPubMed
4. Doria, R, Jekel, J F, Cooper, D L. Thyroid lymphoma. The case for combined modality therapy. Cancer 1994; 73: 200206.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
5. Smith, A, Howell, D, Patmore, R, Jack, A, Roman, E. Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network. Br J Cancer 2011; 105: 16841692.CrossRefGoogle ScholarPubMed
6. Armitage, J O, Weisenburger, D D. New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project. J Clin Oncol 1998; 16: 27802795.Google Scholar
7. Zucca, E, Roggero, E, Pileri, S. B-cell lymphoma of MALT type: a review with special emphasis on diagnostic and management problems of low-grade gastric tumours. Br J Haematol 1998; 100: 314.CrossRefGoogle ScholarPubMed
8. Rosado, M F, Byrne, G E Jr, Ding, F et al. Ocular adnexal lymphoma: a clinicopathologic study of a large cohort of patients with no evidence for an association with Chlamydia psittaci. Blood 2006; 107: 467472.Google Scholar
9. Isobe, K, Kagami, Y, Higuchi, K et al. A multicenter phase II study of local radiation therapy for stage IEA mucosa-associated lymphoid tissue lymphomas: a preliminary report from the Japan Radiation Oncology Group (JAROG). Int J Radiat Oncol Biol Phys 2007; 69: 11811186.CrossRefGoogle ScholarPubMed
10. Tsang, R W, Gospodarowicz, M K, Pintilie, M et al. Stage I and II MALT lymphoma: results of treatment with radiotherapy. Int J Radiat Oncol Biol Phys 2001; 50: 12581264.Google Scholar
11. Onal, C, Li, Y X, Miller, R C et al. Treatment results and prognostic factors in primary thyroid lymphoma patients: a rare cancer network study. Ann Oncol 2011; 22: 156164.CrossRefGoogle ScholarPubMed
12. Watanabe, N, Noh, J Y, Narimatsu, H et al. Clinicopathological features of 171 cases of primary thyroid lymphoma: a long-term study involving 24553 patients with Hashimoto's disease. Brit J Haematol 2011; 153: 236243.Google Scholar
13. Colovic, M, Matic, S, Kryeziu, E, Tomin, D, Colovic, N, Atkinson, H D. Outcomes of primary thyroid non-Hodgkin's lymphoma: a series of nine consecutive cases. Med Oncol 2007; 24: 203208.CrossRefGoogle ScholarPubMed
14. Cheng, V, Brainard, J, Nasr, C. Co-occurrence of papillary thyroid carcinoma and primary lymphoma of the thyroid in a patient with long-standing Hashimoto's thyroiditis. Thyroid 2012; 22: 647650.CrossRefGoogle Scholar
15. Melo, G M, Sguilar, D A, Petiti, C M. Concomitant thyroid MALT lymphoma and papillary thyroid carcinoma. Arq Bras Endocrinol Metabol 2010; 54 (4): 425428.Google Scholar
16. Nam, Y J, Kim, B H, Lee, S K. Co-occurrence of papillary thyroid carcinoma and mucosa-associated lymphoid tissue lymphoma in a patient with long-standing Hashimoto thyroiditis. Endocrinol Metab (Seoul) 2013; 28 (4): 341345.Google Scholar