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Differential association of HIV-related neuropsychological impairment with semantic versus repetition priming

Published online by Cambridge University Press:  01 July 1999

PAUL JASIUKAITIS  and
GEORGE FEIN
PAUL JASIUKAITIS
Affiliation:
Department of Psychiatry, University of California San Francisco
GEORGE FEIN
Affiliation:
Department of Psychiatry, University of California San Francisco Department of Radiology, University of California San Francisco Research Service, Veterans Affairs Medical Center, San Francisco, California
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Abstract

There is evidence that the facilitating effects of stimulus repetition (repetition or identity priming) are mediated by visuoperceptual functions local to extrastriate cortex. Semantic or verbal–associative priming, on the other hand, is believed to be a function of more anterior brain systems. The present study finds evidence for disrupted semantic priming with intact repetition priming in a cognitively impaired HIV+ sample. These results are consistent with recent brain-imaging evidence for a subcortical and white-matter locus for HIV associated neuropathology resulting in effects on subcortical–frontal systems. (JINS, 1999, 5, 434–441.)

Keywords

Presemantic systemsExtrastriate cortexSemantic primingSubcortical–frontal systems
Type
Research Article
Information
Journal of the International Neuropsychological Society , Volume 5 , Issue 5 , July 1999 , pp. 434 - 441
Copyright
© 1999 The International Neuropsychological Society

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