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Good Holders, Bad Shufflers: An Examination of Working Memory Processes and Modalities in Children with and without Attention-Deficit/Hyperactivity Disorder

Published online by Cambridge University Press:  17 November 2015

Ashley N. Simone ,
Anne-Claude V. Bédard ,
David J. Marks  and
Jeffrey M. Halperin
Ashley N. Simone
Affiliation:
The Graduate Center, City University of New York, New York
Anne-Claude V. Bédard
Affiliation:
Ontario Institute for Studies in Education, the University of Toronto, Canada
David J. Marks
Affiliation:
Langone Medical Center, New York University, New York
Jeffrey M. Halperin*
Affiliation:
Queens College and The Graduate Center, City University of New York, New York
*
Correspondence and reprint requests to: Jeffrey M. Halperin, Department of Psychology, Queens College, CUNY, 65-30 Kissena Boulevard, Flushing, NY 11367. Email: jeffrey.halperin@qc.cuny.edu
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Abstract

The aim of this study was to examine working memory (WM) modalities (visual-spatial and auditory-verbal) and processes (maintenance and manipulation) in children with and without attention-deficit/hyperactivity disorder (ADHD). The sample consisted of 63 8-year-old children with ADHD and an age- and sex-matched non-ADHD comparison group (N=51). Auditory-verbal and visual-spatial WM were assessed using the Digit Span and Spatial Span subtests from the Wechsler Intelligence Scale for Children Integrated - Fourth Edition. WM maintenance and manipulation were assessed via forward and backward span indices, respectively. Data were analyzed using a 3-way Group (ADHD vs. non-ADHD)×Modality (Auditory-Verbal vs. Visual-Spatial)×Condition (Forward vs. Backward) Analysis of Variance (ANOVA). Secondary analyses examined differences between Combined and Predominantly Inattentive ADHD presentations. Significant Group×Condition (p=.02) and Group×Modality (p=.03) interactions indicated differentially poorer performance by those with ADHD on backward relative to forward and visual-spatial relative to auditory-verbal tasks, respectively. The 3-way interaction was not significant. Analyses targeting ADHD presentations yielded a significant Group×Condition interaction (p=.009) such that children with ADHD-Predominantly Inattentive Presentation performed differentially poorer on backward relative to forward tasks compared to the children with ADHD-Combined Presentation. Findings indicate a specific pattern of WM weaknesses (i.e., WM manipulation and visual-spatial tasks) for children with ADHD. Furthermore, differential patterns of WM performance were found for children with ADHD-Predominantly Inattentive versus Combined Presentations. (JINS, 2016, 22, 1–11)

Keywords

Attention-deficit hyperactivity disorderWorking memoryVisual-spatialAuditory-verbalMaintenanceManipulation
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 22 , Issue 1 , January 2016 , pp. 1 - 11
Copyright
Copyright © The International Neuropsychological Society 2015 

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References

American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed. Text Revision). Washington, DC: American Psychiatric Association.Google Scholar
American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington DC: American Psychiatric Association.Google Scholar
Baddeley, A.D. (2000). The episodic buffer: A new component of working memory. Trends in Cognitive Sciences, 4, 417–423. doi:10.1016/S1364-6613(00)01538-2 Google Scholar
Baddeley, A.D. (2012). Working memory: Theories, models, and controversies. Annual Review of Psychology, 63, 1–29. doi: 10.1146/annurev-psych-120710-100422 Google Scholar
Baddeley, A.D., & Hitch, G. (1974). Working memory. Psychology of Learning and Motivation, 8, 47–89. doi:10.1016/S0079-7421(08)60452-1 Google Scholar
Barkley, R.A. (1997). Behavioral inhibition, sustained attention, and executive function: Constructing a unified theory of ADHD. Psychological Bulletin, 121, 65–94. 10.1037/0033-2909.121.1.65 Google Scholar
Bedard, A.-C., Martinussen, R., Ickowicz, A., & Tannock, R. (2004). Methylphenidate improves visual-spatial memory in children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 43(3), 260–280. doi:10.1097/00004583-200403000-00006 CrossRefGoogle ScholarPubMed
Berwid, O.G., Curko Kera, E.A., Marks, D.J., Santra, A., Bender, H.A., & Halperin, J.M. (2005). Sustained attention and response inhibition in young children at risk for Attention Deficit/Hyperactivity Disorder. Journal of Child Psychology and Psychiatry, 46(11), 1219–1229.Google Scholar
Chacko, A., Bedard, A.-C., Marks, D.J., Feirsen, N., Uderman, J.Z., Chimiklis, A., & Ramon, M. (2014). A randomized clinical trial of Cogmed working memory training in school-age children with ADHD: A replication in a diverse sample using a control condition. Journal of Child Psychology and Psychiatry, 55(3), 247–255. doi:10.1111/jcpp.12146 Google Scholar
de Jong, C.G.W., Van De Voorde, S., Roeyers, H., Raymakers, R., Oosterlaan, J., & Sergeant, J.A. (2009). How distinctive are ADHD and RD? Results of a double dissociation study. Journal of Abnormal Child Psychology, 37, 1007–1017. doi:10.1007/s10802-009-9328-y Google Scholar
Delis, D.C., Kaplan, E., & Kramer, J.H. (2001). D-KEFS. San Antonio, TX: Psychological Corporation.Google Scholar
Dennis, M., Francis, D.J., Cirino, P.T., Schachar, R., Barnes, M.A., & Fletcher, J.M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. Journal of the International Neuropsychological Society, 15(3), 331–343. doi:10.1017/S1355617709090481 CrossRefGoogle Scholar
Dovis, S., Van der Oord, S., Wiers, R.W., & Prins, P.J.M. (2012). Can motivation normalize working memory and task persistence in children with attention-deficit/hyperactivity disorder? The effects of money and computer-gaming. Journal of Abnormal Child Psychology, 40, 669–681. doi:10.1007/s10802-011-9601-8 Google Scholar
Dovis, S., Van der Oord, S., Wiers, R.W., & Prins, P.J.M. (2013). What part of working memory is not working in ADHD? Short-term memory, the central executive and effects of reinforcement. Journal of Abnormal Child Psychology, 41, 901–917. doi:10.1007/s10802-013-9729-9 CrossRefGoogle Scholar
DuPaul, G.J., Power, T.J., Anastopoulus, A.D., & Reid, R. (1998). ADHD-Rating Scale-IV (for children and adolescents): Checklists, norms, and clinical interpretation. New York: Guilford Press.Google Scholar
Engle, R.W., Tuholski, S.W., Laughlin, J.E., & Conway, A.R. (1999). Working memory, short-term memory, and general fluid intelligence: A latent-variable approach. Journal of Experimental Psychology General, 128(3), 309–331. doi:10.1037/0096-3445.128.3.309 Google Scholar
Fair, D.A., Bathula, D., Nikolas, M.A., & Nigg, J.T. (2012). Distinct neuropsychological subgroups in typically-developing youth inform heterogeneity in children with ADHD. Proceedings of the National Academy of Sciences of the United States of America, 109, 6769–6774. doi:10.1073/pnas.1115365109 Google Scholar
Ferrin, M., & Vance, A. (2012). Examination of neurological subtle signs in ADHD as a clinical tool for the diagnosis and their relationship to spatial working memory. Journal of Child Psychology and Psychiatry, 53, 290–400. doi:10.1111/j.1469-7610.2011.02496.x.CrossRefGoogle ScholarPubMed
Fried, R., Hirshfield-Becker, D., Petty, C., Batchelder, H., & Biederman, J. (2012). How informative is the CANTAB to assess executive functioning in children with ADHD? A controlled 71 study. Journal of Attention Disorders doi:10.1177/1087054712457038 Google Scholar
Gau, S.S., & Chiang, H. (2013). Association between early attention-deficit/hyperactivity symptoms and current verbal and visuo-spatial short-term memory. Research in Developmental Disabilities, 34, 710–720. doi:10.1016/j.ridd.2012.10.005 CrossRefGoogle ScholarPubMed
Gau, S.S., Chiu, C.D., Shang, C.Y., Cheng, A.T., & Soong, W.T. (2009). Executive function in adolescence among children with attention-deficit/hyperactivity disorder in Taiwan. Journal of Developmental & Behavioral Pediatrics, 30(6), 525–534. doi:10.1097/DBP.0b013e3181c21c97 Google Scholar
Healey, D., & Rucklidge, J.J. (2006). An investigation into the relationship among ADHD symptomatology, creativity, and neuropsychological functioning in children. Child Neuropsychology, 12(6), 421–438. doi:10.1080/09297040600806086 Google Scholar
Kaplan, E., Fein, D., Kramer, J., Morris, R., Delis, D., & Maerlender, A. (2004). Wechsler Intelligence Scale for Children – Fourth Edition Integrated (WISC-IV Integrated). San Antonio, TX: The Psychological Corporation.Google Scholar
Karalunas, S.L., & Huang-Pollock, C.L. (2013). Integrating impairments in reaction time and executive function using a diffusion model framework. Journal of Abnormal Child Psychology, 41, 837–850. doi:10.1007/s10802-013-9715-2 Google Scholar
Kasper, L.J., Alderson, R.M., & Hudec, K.L. (2012). Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): A meta-analytic review. Clinical Psychology Review, 32, 605–617. doi:10.1016/j.cpr.2012.07.001 Google Scholar
Kaufman, J., Birmaher, B., Brent, D., Rao, U., & Ryan, N. (1996). The schedule for affective disorders and schizophrenia for school-aged children and lifetime version (version 1.0). Pittsburgh, PA: Department of Psychiatry, University of Pittsburgh School of Medicine.Google Scholar
Kerns, K.A., McInerney, R.J., & Wilde, N.J. (2001). Time reproduction, working memory, and behavioral inhibition in children with ADHD. Child Neuropsychology, 7(1), 21–31. doi:10.1076/chin.7.1.21.3149 Google Scholar
Klingberg, T. (2010). Training and plasticity of working memory. Trends in Cognitive Sciences, 14, 317–324. doi:10.1016/j.tics.2010.05.002 Google Scholar
Klingberg, T., Fernell, E., Olesen, P., Johnson, M., Gustafsson, P., Dahlstrom, K., & Westerberg, H. (2005). Computerized training of working memory in children with ADHD- A randomized, controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 177–186. doi:10.1097/00004583-200502000-00010 Google Scholar
Lord, F.M. (1967). A paradox in the interpretation of group comparisons. Psychological Bulletin, 68, 304–305.Google Scholar
Manassis, K., Tannock, R., Young, A., & Francis-John, S. (2007). Cognition in anxious children with attention deficit hyperactivity disorder: A comparison with clinical and normal children. Behavioral and Brain Functions, 3(4), 1–10. doi:10.1186/1744-9081-3-4 Google Scholar
Marks, D.J., Berwid, O.G., Santra, A., Kera, E.A., Cyrulnik, S.E., & Halperin, J.M. (2005). Neuropsychological correlates of AD/HD symptoms in preschoolers. Neuropsychology, 19, 446–455.Google Scholar
Martinussen, R., Hayden, J., & Hogg-Johnson, S.T.R. (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 44, 377–384. doi:10.1097/01.chi.0000153228.72591.73 CrossRefGoogle ScholarPubMed
McInnes, A., Humphries, T., Hogg-Johnson, S., & Tannock, R. (2003). Listening comprehension and working memory are impaired in attention-deficit hyperactivity disorder irrespective of language impairment. Journal of Abnormal Child Psychology, 31, 427–443. doi:10.1023/A:1023895602957 Google Scholar
Miles, J., & Shevlin, M. (2001). Applying regression and correlation: A guide for students and researchers. London: Sage.Google Scholar
Miller, G.A., & Chapman, J.P. (2001). Misunderstanding analysis of covariance. Journal of Abnormal Psychology, 110(1), 40–48. doi:10.1037/0021-843X.110.1.40 CrossRefGoogle ScholarPubMed
Myatchin, I., Lemiere, J., Danckaerts, M., & Lagae, L. (2012). Within-subject variability during spatial working memory in children with ADHD: An event-related potentials study. European Child and Adolescent Psychiatry, 21, 199–210. doi:10.1007/s00787-012-0253-1 Google Scholar
Nakao, K., & Treas, J. (1994). Updating occupational prestige and socioeconomic scores: How the new measures measure up. Sociological Methodology, 24, 1–72.Google Scholar
Nikolas, M.A., & Nigg, J.T. (2013). Neuropsychological performance and attention-deficit hyperactivity disorder subtypes and symptom dimensions. Neuropsychology, 27, 107–120. doi: 10.1037/a0030685 Google Scholar
Nyman, A., Taskinen, T., Gronroos, M., Haataja, L., Landetie, J., & Korhonen, T. (2010). Elements of working memory as predictors of goal-setting in children with attention-deficit hyperactivity disorder. Journal of Learning Disabilities, 43(6), 553–562. doi:10.1177/0022219410375001 CrossRefGoogle ScholarPubMed
Oosterlaan, J., Logan, G.D., & Sergeant, J.A. (1998). Response inhibition in AD/HD, CD, comorbid AD/HD+CD, and control children: A meta-analysis of studies with the stop task. Journal of Child Psychology and Psychiatry, 39(3), 411–425.Google Scholar
Rajendran, K., Trampush, J.W., Rindskopf, D., Marks, D.J., O’Neill, S., & Halperin, J.M. (2013). Association between variation in neuropsychological development and trajectory of ADHD severity in early childhood. American Journal of Psychiatry, 170, 1205–1211. doi:10.1176/appi.ajp.2012.12101360 Google Scholar
Rapport, M.D., Alderson, R.M., Kofler, M.J., Sarver, D.E., Bolden, J., & Sims, V. (2008). Working memory deficits in boys with attention-deficit/hyperactivity disorder (ADHD): The contribution of central executive and subsystem processes. Journal of Abnormal Child Psychology, 36, 825–837. doi:10.1007/s10802-008-9215-y Google Scholar
Rapport, M.D., Orban, S.A., Kofler, M.J., & Friedman, L.M. (2013). Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta-analytic review of cognitive, academic, and behavioral outcomes. Clinical Psychology Review, 33(8), 1237–1252. doi:10.1016/j.cpr.2013.08.005 Google Scholar
Rhodes, S.M., Park, J., Seth, S., & Coghill, D.R. (2012). A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder. Journal of Child Psychology and Psychiatry, 53, 128–137. doi:10.1111/j.1469-7610.2011.02436.x Google Scholar
Robbins, T.W., James, M., Owen, A.M., Sahakian, B.J., McInnes, L., & Rabbitt, P. (1994). Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers. Dementia, 5, 266–281. doi:10.1159/000106735 Google Scholar
Rommelse, N.N., Altink, M.E., de Sonneville, L.M., Buschgens, C.J., Buitelaar, J., Oosterlaan, J., & Sergeant, J.A. (2007). Are motor inhibition and cognitive flexibility dead ends in ADHD? Journal of Abnormal Child Psychology, 35(6), 957–967.Google Scholar
Sergeant, J., Geurts, H., & Oosterlaan, J. (2002). How specific is a deficit of executive functioning for attention-deficit/hyperactivity disorder? Behavioural Brain Research, 130, 3–28.Google Scholar
Seidman, L.J., Valera, E.M., Makris, N., Monuteaux, M.C., Boriel, D.L., Kelkar, K., & Biederman, J. (2006). Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging. Biological Psychiatry, 60, 1071–1080.Google Scholar
Shaw, P., Eckstrand, K., Sharp, W., Blumenthal, J., Lerch, J.P., Greenstein, D., & Rapoport, J.L. (2007). Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proceedings of the National Academy of Sciences of the United States of America, 104(49), 19649–19654. doi:10.1073/pnas.0707741104 Google Scholar
Simmonds, D.J., Hallquist, M.N., Asato, M., & Luna, B. (2014). Developmental stages and sex differences of white matter and behavioral development through adolescence: A longitudinal diffusion tensor imaging (DTI) study. Neuroimage, 92, 356–368. doi:10.1016/j.neuroimage.2013.12.044 Google Scholar
Sjöwall, D., Roth, L., Lindqvist, S., & Thorell, L.B. (2013). Multiple deficits in ADHD: Executive dysfunction, delay aversion, reaction time variability, and emotional deficits. Journal of Child Psychology and Psychiatry, 54(6), 619–627. doi:10.1111/jcpp.12006 Google Scholar
Skogli, E.W., Egeland, J., Andersen, P.N., Hovik, K.T., & Øie, M. (2013). Few differences in hot and cold executive functions in children and adolescents with combined and inattentive subtypes of ADHD. Child Neuropsychology, 20(2), 162–181. doi:10.1080/09297049.2012.753998 Google Scholar
Solanto, M.V., Gilbert, S.N., Raj, A., Zhu, J., Pope-Boyd, S., Stepak, B., & Newcorn, J.H. (2007). Neurocognitive functioning in AD/HD, predominantly inattentive and combined subtypes. Journal of Abnormal Child Psychology, 35(5), 729–744. doi:10.1007/s10802-007-9123-6 Google Scholar
Sternberg, S. (1969). The discovery of processing stages: Extensions of Donders’ method. Acta Psychologica Attention and Performance II, 30, 276–315.CrossRefGoogle Scholar
Strand, M.T., Hawk, L.W. Jr., Bubnik, M., Shiels, K., Pelham, W.E. Jr., & Waxmonsky, J.G. (2012). Improving working memory in children with attention-deficit/hyperactivity disorder: The separate and combined effects of incentives and stimulant medication. Journal of Abnormal Child Psychology, 40, 1193–1207. doi:10.1007/s10802-012-9627-6 Google Scholar
Takács, Á., Kóbor, A., Tárnok, Z., & Csépe, V. (2014). Verbal fluency in children with ADHD: Strategy using and temporal properties. Child Neuropsychology, 20(4), 415–429. doi:10.1080/09297049.2013.799645 Google Scholar
Tseng, W., & Gau, S.S. (2013). Executive function as a mediator in the link between attention-deficit/hyperactivity disorder and social problems. Journal of Child Psychology and Psychiatry, 54(9), 996–1004. doi:10.1111/jcpp.12072 Google Scholar
Udal, A.H., Øygarden, B., Egeland, J., Malt, E.F., Løvdahl, H., Pripp, A.H., & Grøholt, B. (2012a). Executive deficits in early onset bipolar disorder versus ADHD: Impact of processing speed and lifetime psychosis. Clinical Child Psychology and Psychiatry, 18, 284–299. doi:10.1177/1359104512455181 CrossRefGoogle ScholarPubMed
Udal, A.H., Øygarden, B., Egeland, J., Malt, E.F., & Grøholt, B. (2012b). Memory in early onset bipolar disorder and attention-deficit/hyperactivity disorder: Similarities and differences. Journal of Abnormal Child Psychology, 40, 1179–1192. doi:10.1007/s10802-012-9631-x Google Scholar
van der Meere, J., & Sergeant, J. (1987). A divided attention experiment with pervasively hyperactive children. Journal of Abnormal Child Psychology, 15(3), 379–391.Google Scholar
van Dongen-Boomsma, M., Vollebregt, M.A., Buitelaar, J.K., & Slaats-Willemse, D. (2014). Working memory training in young children with ADHD: A randomized placebo-controlled trial. Journal of Child Psychology and Psychiatry, 55(8), 886–896. doi:10.1111/jcpp.12218 Google Scholar
Vance, A., Ferrin, M., Winther, J., & Gomez, R. (2013). Examination of spatial working memory performance in children and adolescents with attention deficit hyperactivity disorder, combined type (ADHD-CT) and anxiety. Journal of Abnormal Child Psychology, 41, 891–900. doi:10.1007/s10802-013-9721-4 Google Scholar
Wager, T.D., & Smith, E.E. (2003). Neuroimaging studies of working memory: A meta-analysis. Cognitive and Affective Behavioral Neuroscience, 3(4), 255–274.Google Scholar
Ware, A.L., Crocker, N., O’Brien, J.W., Deweese, B.N., Roesch, S.C., & Coles, C.D., CIFASD (2012). Executive function predicts adaptive behavior in children with histories of heavy prenatal alcohol exposure and attention-deficit/hyperactivity disorder. Alcoholism: Clinical and Experimental Research, 36, 1431–1441. doi:10.1111/j.1530-0277.2011.01718.x Google Scholar
Wechsler, D. (2001). Wechsler Individual Achievement Test – Second Edition (WIAT-II). San Antonio, TX: The Psychological Corporation.Google Scholar
Wechsler, D. (2006). Wechsler Preschool and Primary Scale of Intelligence- Third Edition (WPPSI-III). San Antonio, TX: The Psychological Corporation.Google Scholar
Wechsler, D. (2003). Wechsler Intelligence Scale for Children—Fourth Edition. San Antonio, TX: The Psychological Corporation.Google Scholar
Willcutt, E.G., Doyle, A.E., Nigg, J.T., Faraone, S.V., & Pennington, B.F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: A meta-analytic review. Biological Psychiatry, 57, 1336–1346. doi:10.1016/j.biopsych.2005.02.006 Google Scholar
Yang, P., Cheng, C., Chang, C., Liu, T., Hsu, H., & Yen, C. (2013). Wechsler Intelligence Scale for Children 4th edition-Chinese version index scores in Taiwanese children with attention-deficit/hyperactivity disorder. Psychiatry and Clinical Neurosciences, 67, 83–91. doi:10.1111/pcn.12014 Google Scholar