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Predicting Fatigue 12 Months after Child Traumatic Brain Injury: Child Factors and Postinjury Symptoms

Published online by Cambridge University Press:  04 October 2017

Alison Crichton ,
Ed Oakley ,
Franz E Babl ,
Mardee Greenham ,
Stephen Hearps ,
Carmel Delzoppo ,
Miriam H. Beauchamp ,
James S. Hutchison ,
Anne-Marie Guerguerian  and
Kathy Boutis
...Show all authors
Alison Crichton*
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia Victorian Pediatric Rehabilitation Service, Monash Children’s, Melbourne, VIC, Australia School of Psychological Sciences, University of Melbourne, VIC Australia
Ed Oakley
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia Department of Pediatrics, University of Melbourne, Melbourne, VIC Australia Royal Children’s Hospital, Melbourne, VIC, Australia
Franz E Babl
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia Department of Pediatrics, University of Melbourne, Melbourne, VIC Australia Royal Children’s Hospital, Melbourne, VIC, Australia
Mardee Greenham
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia School of Psychological Sciences, University of Melbourne, VIC Australia
Stephen Hearps
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia
Carmel Delzoppo
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia Royal Children’s Hospital, Melbourne, VIC, Australia
Miriam H. Beauchamp
Affiliation:
Department of Psychology, University of Montreal, Montreal, Canada Research Center, Ste-Justine Hospital, Montreal, Canada
James S. Hutchison
Affiliation:
The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada Neuroscience and Mental Health Research Program, SickKids Research Institute, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada
Anne-Marie Guerguerian
Affiliation:
The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada
Kathy Boutis
Affiliation:
The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada
Vicki Anderson
Affiliation:
Murdoch Childrens Research Institute, Melbourne, Australia School of Psychological Sciences, University of Melbourne, VIC Australia Royal Children’s Hospital, Melbourne, VIC, Australia
*
Correspondence and reprint requests to: Alison Crichton, Murdoch Childrens Research Institute, 50 Flemington Road, Parkville, Victoria, 3052, Australia. E-mail: ali.crichton@mcri.edu.au
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Abstract

Objectives: Fatigue is a common and persisting symptom after childhood brain injury. This study examined whether child characteristics and symptomatology preinjury or 6 months postinjury (pain, sleep, and mood, inattention) predicted fatigue at 12months postinjury. Methods: Parents of 79 children (0–18 years) rated fatigue at 12 months after injury on a multidimensional scale (general, sleep/rest, and cognitive). Demographic and clinical data were collected at injury. Parents rated child sleep, pain, physical/motor function, mood, and inattention at injury (preinjury description), and 6 months postinjury. Children were divided into two traumatic brain injury severity groups: mild TBI (n=57) and moderate/severe TBI (n=27). Hierarchical regression models were used to examine (i) preinjury factors and (ii) symptoms 6 months postinjury predictive of fatigue (general, sleep/rest, and cognitive) at 12 months postinjury. Results: Sleep/rest fatigue was predicted by preinjury fatigue (7% of variance) and psychological symptoms preinjury (10% of variance). General fatigue was predicted by physical/motor symptoms (27%), sleep (10%) and mood symptoms (9%) 6 months postinjury. Sleep/rest fatigue was predicted by physical/motor symptoms (10%), sleep symptoms (13%) and mood symptoms (9%) 6 months postinjury. Cognitive fatigue was predicted by physical/motor symptoms (17%) 6 months postinjury. Conclusions: Preinjury fatigue and psychological functioning identified those at greatest risk of fatigue 12 months post-TBI. Predictors of specific fatigue domains at 12 months differed across each of the domains, although consistently included physical/motor function as well as sleep and mood symptoms postinjury. (JINS, 2018, 24, 224–236)

Keywords

Mental fatigueMuscle fatigueBrain concussionAdolescentChildrenRegression modelsLongitudinal studies
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 24 , Issue 3 , March 2018 , pp. 224 - 236
Copyright
Copyright © The International Neuropsychological Society 2017 

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