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The Effect of Bacteria on Epidermal WoundHealing

Published online by Cambridge University Press:  28 April 2010

E. Agyingi ,
S. Maggelakis  and
D. Ross
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Abstract

Epidermal wound healing is a complex process that repairs injured tissue. The complexityof this process increases when bacteria are present in a wound; the bacteria interactiondetermines whether infection sets in. Because of underlying physiological problemsinfected wounds do not follow the normal healing pattern. In this paper we present amathematical model of the healing of both infected and uninfected wounds. At the core ofour model is an account of the initiation of angiogenesis by macrophage-derived growthfactors. We express the model as a system of reaction-diffusion equations, and we presentresults of computations for a version of the model with one spatial dimension.

Keywords

wound healingangiogenesisgrowth factorsbacteria infection
Type
Research Article
Information
Mathematical Modelling of Natural Phenomena , Volume 5 , Issue 3: Mathematical modeling in the medical sciences , 2010 , pp. 28 - 39
Copyright
© EDP Sciences, 2010

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