Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-10T06:35:15.309Z Has data issue: false hasContentIssue false
  • English
  • Français

Characterization of Hydroxyapatite Coated Mg for Biomedical Applications

Published online by Cambridge University Press:  01 June 2018

Jiajia Lin ,
Qiaomu Tian ,
Arash Aslani  and
Huinan Liu
Jiajia Lin
Affiliation:
Materials Science & Engineering Program, University of California, Riverside CA92521USA
Qiaomu Tian
Affiliation:
Department of Bioengineering, University of California, Riverside CA92521USA
Arash Aslani
Affiliation:
N2 Biomedical LLC, One Patriots Park, Bedford, MA01730, USA
Huinan Liu*
Affiliation:
Materials Science & Engineering Program, University of California, Riverside CA92521USA Department of Bioengineering, University of California, Riverside CA92521USA Biomedical Sciences Program, School of Medicine, University of California, Riverside CA92521USA
*
*(Email: huinanliu@engr.ucr.edu)
Get access

Abstract:

Magnesium (Mg) and its alloys have showed a promising potential for medical implant applications due to their attractive biocompatibility and mechanical strength. Despite these promising properties, the critical challenge with Mg-based implants is rapid degradation in physiological environment that results in early loss of mechanical strength and hydrogen gas accumulation at the local site. Hydroxyapatite (HA) coatings provide a sound solution for controlling Mg degradation at the bone interface. In this paper, HA coatings with different particle sizes, namely, microHA (mHA) and nanoHA (nHA), were deposited on Mg plates and rods with two different pressures using N2 Biomedical’s proprietary deposition process called IonTiteTM. Surface characterization of the deposited layers showed mHA coated Mg prepared at high pressure had more homogeneous HA particles distribution with less defects.

Keywords

coatingMgmicrostructurenanostructure
Type
Articles
Information
MRS Advances , Volume 3 , Issue 40: Soft Materials and Biomaterials , 2018 , pp. 2385 - 2389
Copyright
Copyright © Materials Research Society 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Staiger, M. P., Pietak, A. M., Huadmai, J., and Dias, G., Biomaterials 27, 1728–1734 (2006).CrossRefGoogle ScholarPubMed
Witte, F., Hort, N., Vogt, C., Cohen, S., Kainer, K. U., Willumeit, R., and Feyerabend, F., Curr. Opin. Solid State Mater. Sci. 12, 63–72 (2008).CrossRefGoogle Scholar
Zheng, Y., Gu, X., and Witte, F., Mater. Sci. Eng. R Rep. 77, 1–34 (2014).CrossRefGoogle Scholar
Hermawan, H., Dubé, D., and Mantovani, D., Acta Biomater. 6, 1693–1697 (2010).CrossRefGoogle Scholar
Cipriano, A. F., Lin, J., Miller, C., Lin, A., Alcaraz, M. C. C., Soria, P. Jr, and Liu, H., Acta Biomater. 62, 397–417 (2017).CrossRefGoogle Scholar
Shadanbaz, S., and Dias, G. J., Acta Biomater. 8, 20–30 (2012).CrossRefGoogle Scholar
Tian, Q., Rivera-Castaneda, L., and Liu, H., Mater. Lett. 186, 12–16 (2017).CrossRefGoogle Scholar
Iskandar, M. E., Aslani, A., and Liu, H., J. Biomed. Mater. Res. A 101, 2340–2354 (2013).CrossRefGoogle Scholar
Webster, T. J., Ergun, C., Doremus, R. H., Siegel, R. W., and Bizios, R., Biomaterials 21, 1803–1810 (2000).CrossRefGoogle Scholar
Wang, H., Guan, S., Wang, X., Ren, C., and Wang, L., Acta Biomater. 6, 1743–1748 (2010).CrossRefGoogle Scholar
Narayanan, T. S., Park, I.-S., and Lee, M.-H., Surface Modification of Magnesium and Its Alloys for Biomedical Applications, 1st ed. (Elsevier, 2015) p. 268.Google Scholar