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Investigating the Function of Ion Channels in Tethered Lipid Membranes by Impedance Spectroscopy

Published online by Cambridge University Press:  31 January 2011

Samuel Terrettaz  and
Horst Vogel
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Abstract

The function of biologically important ion channels can be measured in supported lipid membranes by impedance spectroscopy. This approach offers substantial advantages over traditional electrophysiological measurements. In this article, we present an overview of the field, with a special emphasis on the reconstitution of ion channels in lipid bilayers tethered to gold electrodes and the modulation of their channel activity by specific ligand binding.

Keywords

biosensorsimpedance spectroscopyion channelssupported lipid bilayerstethered membranes
Type
Research Article
Information
MRS Bulletin , Volume 30 , Issue 3: Biointerface Science , March 2005 , pp. 207 - 210
Copyright
Copyright © Materials Research Society 2005

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