Published online by Cambridge University Press: 10 August 2017
The holy grail of regenerative technologies is to regrow a limb. This grand challenge requires us to develop truly innovative strategies and toolboxes across advanced materials science, stem cell science, physics, and developmental biology, and converge these advancements to address the limitations of wound healing and harness the regenerative capacity in humans. We discuss the convergence approach put forward by the field of regenerative engineering to develop translational strategies involving electrically conductive and novel polymers, stem cells, high-throughput technologies, and nanotechnology to regenerate the limb.