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3ω Measurements for Tracking Freezing Fronts in Biological Applications

Published online by Cambridge University Press:  15 July 2015

Wyatt Hodges ,
Harishankar Natesan ,
John Bischof  and
Chris Dames
Wyatt Hodges
Affiliation:
Department of Mechanical Engineering, University of California, Berkeley
Harishankar Natesan
Affiliation:
Department of Mechanical Engineering University of Minnesota
John Bischof
Affiliation:
Department of Mechanical Engineering University of Minnesota
Chris Dames
Affiliation:
Department of Mechanical Engineering, University of California, Berkeley
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Abstract

One approach to treating atrial fibrillation relies on freezing tissue of the heart wall. This surgical technology requires sub-millimeter spatial resolution when dynamically tracking the freezing of pulmonary vein; conventional techniques such as ultrasound lack the necessary precision. Here we use an electrothermal “3ω” method to track propagating freezing fronts in nearly real time. The heater line is excited with multiple frequencies simultaneously, and the freezing front detected as it passes through the various penetration depths due to the contrast between thermal conductivities on either side of the front. Comparison of water freezing experiments with video images further suggests the accuracy of the method. Analysis and experiments show how the uncertainty, time response, and measurement range depend on the frequencies and thermal conductivity contrast. Finally, the method is demonstrated on biological tissue as further proof of principle for medical applications.

Keywords

thermal conductivitybiomedicalwater
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1779: Symposium M – Nanoscale Heat Transport―From Fundamentals to Devices , 2015 , pp. 15 - 20
Copyright
Copyright © Materials Research Society 2015 

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References

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