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Correlated Single Molecule Fluorescence and Scanning Probe Microscopies: Applications to the Study of Soft Materials

Published online by Cambridge University Press:  01 February 2011

Andrea L. Slade ,
James E. Shaw ,
Guocheng Yang ,
Neetu Chhabra  and
Christopher M. Yip
Andrea L. Slade
Affiliation:
Department of Biochemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9
James E. Shaw
Affiliation:
Department of Biochemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9
Guocheng Yang
Affiliation:
Department of Chemical Engineering and Applied Chemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9
Neetu Chhabra
Affiliation:
Department of Chemical Engineering and Applied Chemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9
Christopher M. Yip
Affiliation:
Department of Biochemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9 Department of Chemical Engineering and Applied Chemistry, , University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9 Institute of Biomaterials and Biomedical Engineering, University of Toronto, 407–4 Taddle Creek Rd, oronto, Ontario, Canada M5S 3G9
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Abstract

We recently developed an integrated imaging platform that combines single molecule evanescent wave fluorescence imaging (and spectroscopy) with in situ scanning probe microscopy. The advantages, challenges, and potential represented by this coupled tool will be described in the context of the structure-function characteristics of nanostructured biomaterials and thin lipid films.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 844: Symposium Y – Mechanical Properties of Bio-Inspired and Biological Materials , 2004 , Y2.1/R2.1
Copyright
Copyright © Materials Research Society 2005

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