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Histological and Mechanical Evaluation of the in vivo Bone-bonding Ability on the K2TinO2n+1/β-Ti Alloy as a Novel Bioactive Material

Published online by Cambridge University Press:  31 January 2011

Chunxiang Cui ,
Y. M. Qi ,
M. F. Zhang ,
J. G. Li ,
S. J. Liu ,
X. L. Xue  and
N. Huang
Chunxiang Cui
Affiliation:
hutcui@hebut.edu.cn, Hebei University of Technology, School of Materials Science & Engineering, Dingzigu, Road No. 1, Hongqiao District, Tianjin 300130, China, Tianjin, Tianjin, 300130, China, 86-22-60204125, 86-22-26564125
Y. M. Qi
Affiliation:
ymqi@hebut.edu.cn, Hebei University of Technology, School of Materials Science & Engineering, Tianjin, China
M. F. Zhang
Affiliation:
mingfangzhang@tmu.edu.cn, Tianjin Medical University, Department of Pathology, Tianjin, China
J. G. Li
Affiliation:
jianguangli6271@126.com, Tianjin Hospital, Department of Spine Surgery, Tianjin, China
S. J. Liu
Affiliation:
liushuangjin@hebut.edu.cn, Hebei University of Technology, School of Materials Science & Engineering, Tianjin, China
X. L. Xue
Affiliation:
xuexuelianllj@163.com, Hebei University of Technology, School of Materials Science & Engineering, Tianjin, China
N. Huang
Affiliation:
nanhuangtj@163.com, Hebei University of Technology, School of Materials Science & Engineering, Tianjin, China
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Abstract

The purpose of this study was to histologically and mechanically appraise the in vivo bone-bonding abilities of K2TinO2n+1 coated and uncoated Ti-15Mo-3Nb (TMN) implants. According to GB/T16886.6－1997 biological evaluation of medical devices Part 6:Tests for local effects after implantation, the two types of implants were implanted into the proximal metaphyses of Chinese white rabbits’ femurs for 12, 26 and 52 weeks and investigated by pushing out test, scanning electron microscopy (SEM) attached to an energy-dispersive X-ray micro-analyzer (EDX) and light microscopy. The bone-bonding abilities of the K2TinO2n+1 biocoating /Ti-15Mo-3Nb (KBT) gradient biomaterial implants were higher than those of T implants at different periods of implantation. The K2TinO2n+1 biocoating (KB) could stimulate new bone rapid formation at the early stages of implantation. And the implants with the biocoating eventually bonded to bone directly, with no intervening soft tissue layer, that was an osseocoalescence. However, the type of bone-bonding between TMN titanium alloy implants and bone was a simple osseocoaptation. The more excellent bone-bonding ability of the KBT implants should be attributed to the superficial characteristics, the bioactivity of low potassium titanate and biostability of high potassium titanate.

Keywords

biomaterialbonecomposite
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1187: Symposium KK – Structure-Property Relationships in Biomineralized and Biomimetic Composites , 2009 , 1187-KK09-06
Copyright
Copyright © Materials Research Society 2009

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