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A Hybrid Laser/Aerosol Method for the Synthesis of Porous Nanostructured Calcium Phosphate Materials for Bone Tissue Engineering Applications

Published online by Cambridge University Press:  01 February 2011

Shatoya Brown ,
Hyunbin Kim  and
Renato P. Camata
Shatoya Brown
Affiliation:
Department of Physics, University of Alabama at Birmingham, Birmingham, AL 35294, U.S.A.
Hyunbin Kim
Affiliation:
Department of Physics, University of Alabama at Birmingham, Birmingham, AL 35294, U.S.A.
Renato P. Camata
Affiliation:
Department of Physics, University of Alabama at Birmingham, Birmingham, AL 35294, U.S.A.
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Abstract

We present a new synthesis method based on laser generation and processing of aerosol particles that can produce calcium phosphate coatings in a porous nanostructured configuration. The process uses laser ablation of crystalline hydroxyapatite targets to produce a calcium phosphate aerosol comprising micro- and nanoparticles that are processed and deposited on metallic substrates under well-controlled temperature and ambient conditions, creating a microporous calcium phosphate network suitable for growth of biogenic calcium phosphate materials. Laser ablation is carried out using a KrF excimer laser at fluences between 0.4 J/cm2 and 2.8 J/cm2 and temperatures ranging from 500°C to 760°C. X-ray diffraction and scanning electron microscopy measurements on samples deposited above 750°C show that the obtained material is crystalline hydroxyapatite with good mechanical stability. Its microstructure features a porous framework of partially sintered microparticles surrounded by nanoparticulate material.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 845: Symposium AA – Nanoscale Materials Science in Biology and Medicine , 2004 , AA5.35
Copyright
Copyright © Materials Research Society 2005

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References

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