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Hydrophilic, heat stable, low protein binding surface modification of PVDF membranes

Published online by Cambridge University Press:  11 February 2011

John Charkoudian
Affiliation:
Millipore Corporation, Bedford, MA 01730, USA
Alex Xenopoulos
Affiliation:
Millipore Corporation, Bedford, MA 01730, USA
John Lynch
Affiliation:
Millipore Corporation, Bedford, MA 01730, USA
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Abstract

Protein binding studies reveal increased levels of protein adsorbed to thermally treated poly-acrylamide-modified PVDF microporous membranes in comparison to polyacrylate-modified membranes. Application of XPS, ToF-SIMS, densitometry and μthermal AFM indicate poly-acryamide-PVDF mixing as the primary cause of the increased protein binding.

Type
Research Article
Copyright
Copyright © Materials Research Society 2003

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References

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