Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-14T19:06:07.317Z Has data issue: false hasContentIssue false
  • English
  • Français

Increased Stem Cell Adhesion on Carbon Nanotubes Grown from Anodized Titanium

Published online by Cambridge University Press:  01 February 2011

Batur Ercan  and
Thomas Webster
Batur Ercan
Affiliation:
batur_ercan@brown.edu, Brown University, Engineering, Barus & Holley 182 Hope St., Box D, Providence, RI, 02906, United States, 765-418-2341
Thomas Webster
Affiliation:
Thomas_Webster@brown.edu, Brown University, Division of Engineering, Barus & Holley 182 Hope St., Box D, Providence, RI, 02912, United States
Get access

Abstract

Stem cells are the source of all differentiated cells in the body. However, the stimuli that control stem cell differentiation into other cell types is still not well understood. In order to investigate this, novel carbon nanotubes (CNT's) were synthesized on anodized titanium substrates by chemical vapor deposition. Human mesenchymal stem cell (HMCS) adhesion was investigated on this nano-structured surface. The results showed significant evidence for the enhancement of HMSC adhesion on carbon nanotubes with respect to the template they were synthesized on, specifically, anodized titanium. Such evidence provides promise for the use of carbon nanotubes grown from anodized titanium to serve as novel stem cell differentiation devices.

Keywords

biomaterialchemical vapor deposition (CVD) (deposition)adhesion
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 951: Symposium E – Nanofunctional Materials, Nanostructures and Novel Devices for Biological and Chemical Detection , 2006 , 0951-E06-28
Copyright
Copyright © Materials Research Society 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Karlsson, M., Palsgard, E., Wilshaw, P.R. and Silvio, L.D., Biomaterials 24, 3039 (2003).Google Scholar
2. Webster, T.J. and Ejiofor, J.U., Biomaterials 25, 19 (2004)Google Scholar
3. Elias, K.L., Price, R.L. and Webster, T.J., Biomaterials 23, 15 (2002)Google Scholar
4. Price, R.L., Waid, M.C., Haberstroh, K.M. and Webster, T.J., Biomaterials 24, 11 (2003)Google Scholar
5. Chua, K.N., Chai, C., Lee, P.C., Tang, Y.N., Ramakrishna, S. and Leong, K.W., Mao, H.Q., Biomaterials, 27, 36 (2006)Google Scholar
6. Batista, S., Guarnieri, D., Borselli, C., Zeppetelli, S., Borzacchiello, A., Mayol, L., Gerbasio, D., Keene, D. R., Ambrosio, L. and Netti, P.A., Biomaterials 26, 31 (2005)Google Scholar
7. Melville, A.J., Harrison, J., Gross, K.A., Forsythe, J.S., Trounson, A.O. and Mollard, R., Biomaterials 27, 4 (2006)Google Scholar
8. Yao, C., Perla, V., McKenzie, J.L., Slamovich, E.B. and Webster, T.J., Journal of Biomedical Nanotechnology, 1, 1 (2005)Google Scholar
9. Yao, C., “Surface modification of titanium by anodization for orthopedic applications”, MS MSE Thesis, Purdue University, (2005)Google Scholar