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Magnetic Resonance Imaging (MRI) of Water Diffusion in 2-Hydroxyethyl Methacrylate (HEMA) Gels

Published online by Cambridge University Press:  01 February 2011

Guy Raguin ,
Cibele V. Falkenberg ,
Shaurya Prakash ,
Heather R. FitzHenry ,
Glennys Mensing ,
Luisa Ciobanu ,
John G. Georgiadis  and
Mark A. Shannon
Guy Raguin
Affiliation:
guy.raguin@mines-nancy.org, Michigan State University, Mechanical Engineering, 2555 Engineering Building, East Lansing, MI, 48824-1226, United States, 517 432-3192, 517 353-1750
Cibele V. Falkenberg
Affiliation:
falkenbe@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244, Urbana, IL, 61801, United States
Shaurya Prakash
Affiliation:
sprakas1@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244, Urbana, IL, 61801, United States
Heather R. FitzHenry
Affiliation:
hfitzhen@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244, Urbana, IL, 61801, United States
Glennys Mensing
Affiliation:
gmensing@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244, Urbana, IL, 61801, United States
Luisa Ciobanu
Affiliation:
lciobanu@bi-staff.beckman.uiuc.edu, University of Illnois at Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Biomedical Imaging Center, 2100 S Goodwin Ave, Urbana, IL, 61801, United States
John G. Georgiadis
Affiliation:
georgia@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244,, Urbana, IL, 61801, United States
Mark A. Shannon
Affiliation:
mshannon@uiuc.edu, University of Illnois at Urbana-Champaign, Mechanical Engineering, 1206 West Green Street,, 140MEB, MC-244, Urbana, IL, 61801, United States
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Abstract

A fundamental study focusing on correlating the local water self-diffusion coefficient to the local free water content in 2-hydroxyethyl methacrylate (HEMA) gels was conducted. HEMA gels were synthesized with different nominal water content (50% to 90%). MRI measurements of local diffusion coefficient distribution and local water content profiles are conducted on a 600 MHz scanner. The local water content is measured via two spin-echo images with sufficiently long repetition time (TR) to eliminate T1-weighting and two values for the echo time (TE) in order to account for T2-weighting. The local diffusion coefficient is determined using a standard pulsed-field gradient spin-echo sequence. The measured local water content and diffusion coefficient data are compared with several single-parameter diffusion models for interstitial diffusion in the hydrogel (Makie-Meares, Stokes-Einstein, Brownian motion around overlapping spheres).

Keywords

diffusionnuclear magnetic resonance (NMR)polymer
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 930: Symposium JJ – Materials Science of Water Purification , 2006 , 0930-JJ04-05
Copyright
Copyright © Materials Research Society 2006

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