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Permeability of CardiothanerR-51 (AvcothanerR-51) and SilasticR 500–1 to Lipophilic Drugs

Published online by Cambridge University Press:  26 February 2011

Stephen D. Bruck  and
M. Kojima
Stephen D. Bruck
Affiliation:
Biomaterials and Medical Devices Consulting Group, Stephen D. Bruck Associates, Inc., P.O. Box 828, Rockville, MD 20851 (To whom all correspondence should be sent)
M. Kojima
Affiliation:
Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, 2-3-10 Surugudai, Kanda, Chiyoda-ku, Tokyo, Japan
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Extract

Sorption processes (adsorption, absorption, permeation) are of considerable importance in the physico-chemical and biological performance of polymeric biomaterials, especially in cardiovascular applications, and in various controlled drug release and drug carrier systems [1,2]. Transport of molecules of widely ranging molecular weights through synthetic as well as biologic membranes represents a basic process in the performance of many medical devices.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 57
Copyright
Copyright © Materials Research Society 1988

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References

1. Bruck, S.D., Properties of Biomaterials in the Physiological Environment, (CRC Press, Boca Raton, Florida, 1980).Google Scholar
2. Bruck, S.D., in: Controlled Drug Delivery, Bruck, S.D., Ed., CRC Press, Boca Raton, Florida 1983, Vol. I - Basic Concepts, Ch. 1, pp. 1–13.Google Scholar
3. Bruck, S.D., Biomaterials, 2, 14 (1981).Google Scholar
4. Ferrans, V.J., Boyce, S.W., Billingham, M.E., Jones, M., Ishihara, T., and Roberts, W.C., Am. J. Cardiol., 46, 721 (1980).Google Scholar
5. Hilbert, S.L., Ferrans, V.J., Tomita, Y., Eidbo, E.E., and Jones, M., J. Thorac Cardiovasc. Surg., 94, 419 (1987).Google Scholar
6. McHenry, M.M., Smeloff, E.A., Fong, W.Y., Miller, G.E. Jr, and Ryan, P.M., J. Thorac. Cardiovasc. Surg., 419 (1987).Google Scholar
7. Bruck, S.D., Kojima, M., Kadoma, Y. and Masuhara, E., Med. Progr. Technol., 10, 161 (1983/1984).Google Scholar
8. Reid, J.S., Rosenberg, G., and Pierce, W.S., J. Biomed. Mat. Res., 19, 1181 (1985).Google Scholar
9. McGee, M.G., Szycher, M., Turner, S.A., Clay, W., Trono, R., Davis, G.L., and Norman, J.C., Trans. Am. Soc. Artif. Intern. Organs, 26, 299 (1980).Google Scholar
10. Bruck, S.D. and Mueller, E.P., Med. Progr. Technol., (in press).Google Scholar
11. Barbaro, V., Bosi, C., Carazza, S., Chistolini, P., lalongo, D., and Rosa, P., Biomaterials, 6, 28 (1985).Google Scholar
12. Lelah, M.D. and Cooper, S.L., Polyurethanes in Medicine, (CRC Press, Boca Raton, Florida, 1986).Google Scholar
13. Coury, A.J., Stokes, K.B., Cahalan, P.T., and Slaikeu, P.C., Life Support Systems, 5, 25 (1987).Google Scholar
14. Stokes, K., in Modern Cardiac Pacing, edited by Barold, S.S., (Futura Publishing Co., Mt. Kisco, NY, 1985), p. 173.Google Scholar
15. Bruck, S.D., in Controlled Drug Delivery, edited by Bruck, S.D. (CRC Press, Inc., Boca Raton, Florida, 1983) Vol. I - Basic Concepts, Ch. 1, p. 1.Google Scholar
16. Bruck, S.D., Rate-Controlled Drug Release System, U.S. Patent No. 4,559,054, December 17, 1985.Google Scholar
17. Bruck, S.D., Kojima, M., Kadoma, Y. and Masuhara, E., Med. Progr. Technol., 10, p. 161 (1983/1984).Google Scholar