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Scaffolds of Collagen from Nukbone ®

Published online by Cambridge University Press:  28 November 2012

Benjamín H. León ,
Miguel A. Araiza  and
M. Cristina Piña
Benjamín H. León
Affiliation:
Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, C.P. 04510, México D.F.
Miguel A. Araiza
Affiliation:
Facultad de Odontología, División de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de México, Cuidad Universitaria, Coyoacán, C.P. 04510, México D.F.
M. Cristina Piña
Affiliation:
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Ciudad Universitaria, Circuito Exterior s/n, Coyoacán, C.P. 04510, México D.F.
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Abstract

The scaffold is obtained from acellular bovine bone: Nukbone® (produced by Biocriss SAPI de CV). This acellular bone was subjected to a demineralization process after which the composition was found to be 10% water, 65% of collagen and 25% of hydroxyapatite. The techniques used to characterize these natural scaffolds were: optical microscopy, scanning electron microscopy, X-ray diffraction, energy dispersive X-ray spectroscopy, thermo gravimetric analysis, differential scanning calorimetry and determination of pore size using nitrogen adsorption, and physical adsorption of N2. The pore size is between 100 and 500 microns. These scaffolds have been tested in several biological tissues as urethra, trachea, blood vessels, bone and heart successfully.

Keywords

BiologicalBiomedicalChemical composition
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1487: Symposium S4B – Biomaterials for Medical Applications-2012 , 2012 , imrc12-s4b-p039
Copyright
Copyright © Materials Research Society 2012 

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References

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