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Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays

Published online by Cambridge University Press:  01 February 2011

Yue Zhao ,
Nidhi Mahajan  and
Jiyu Fang
Yue Zhao
Affiliation:
yu200043@pegasus.cc.ucf.eduUnviersity of Central FloridaAdvanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and AerospaceOrlando FL 32816United States
Nidhi Mahajan
Affiliation:
nidhim@amgen.com, Unviersity of Central Florida, Advanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and Aerospace, Orlando, FL, 32816, United States
Jiyu Fang
Affiliation:
jfang@mail.ucf.edu, Unviersity of Central Florida, Advanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and Aerospace, Orlando, FL, 32816, United States
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Abstract

The rolling of lipid bilayer sheets into hollow cylindrical tubules have emerged as a group of interesting supramolecular nanostructures. Here, we image the self-assembled tubules of 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphochloline (DC8,9PC) with atomic force microscopy. Nanoscale ripple structures with a periodicity of ~ 200nm in the cylindrical lipid tubules are observed. We develop two simple methods based on microfluidic networks and surface patterning to produce two dimensional ordered arrays of parallel aligned lipid tubules on substrates.

Keywords

macromolecular structurescanning probe microscopy (SPM)lithography (deposition)
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 922: Symposium U – Organic and Inorganic Nanotubes – From Molecular to Submicron Structures , 2006 , 0922-U05-02
Copyright
Copyright © Materials Research Society 2006

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