Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-13T13:27:17.244Z Has data issue: false hasContentIssue false
  • English
  • Français

Synthesis of Bioactive Ormosils by the Sol-Gel Method

Published online by Cambridge University Press:  10 February 2011

K. Tsuru ,
C. Ohtsuki ,
A. Osaka ,
T. Iwamoto  and
J. D. Mackenzie
K. Tsuru
Affiliation:
Biomaterials Lab, Faculty of Engineering, Okayama University, Tsushima, Okayama 700 Japan
C. Ohtsuki
Affiliation:
Biomaterials Lab, Faculty of Engineering, Okayama University, Tsushima, Okayama 700 Japan
A. Osaka
Affiliation:
Biomaterials Lab, Faculty of Engineering, Okayama University, Tsushima, Okayama 700 Japan
T. Iwamoto
Affiliation:
Materials Department, School of Applied Science and Engineering, University of California, Los Angeles CA 90024, U.S.A.
J. D. Mackenzie
Affiliation:
Materials Department, School of Applied Science and Engineering, University of California, Los Angeles CA 90024, U.S.A.
Get access

Abstract

Bioactive ORMOSILS (Organically Modified Silicates) were synthesized by a sol-gel method, with tetraethoxysilane (TEOS) and polydimethylsiloxane (PDMS). Ca(II) ions were incorporated into the ormosil monoliths by addition of calcium nitrate. The synthesized samples were examined on the bioactivity by the use of a simulated body fluid (the Kokubo solution). The Ca(II) containing ormosils were bioactive that deposited apatite during soaking in the Kokubo solution. The dissolution of Ca(II) from the sample favored the formation of the hydrated silica, which gave nucleation sites for apatite, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the fluid could not be neglected.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 435: Symposium V – Better Ceramics Through Chemistry VII , 1996 , 403
Copyright
Copyright © Materials Research Society 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

[1] Hench, L. L., Splinter, R. J., Allen, W. C. and Greenlee, T. K., J. Biomed. Mater. Res., 2, 117–141 (1972).Google Scholar
[2] Wilson, J., in Glass-Current Issues, edited by Wright, A. F. and Dupuy, J., (Martinus Nijhoff Publishers, Dordrecht, 1985), pp. 662–669.Google Scholar
[3] Hench, L. L., J. Am. Ceram. Soc., 74, 1487–1510 (1991).Google Scholar
[4] Yamamuro, T., in Introduction to bioceramics, edited by Hench, L. L. and Wilson, J., (World Scientific, Singapore, 1993), pp. 89–103.Google Scholar
[5] Kokubo, T., J. Ceram. Soc. Japan, 99,965–973 (1991).Google Scholar
[6] Ohtsuki, C., Kokubo, T. and Yamamuro, T., J. Non-Cryst. Solids, 143, 84–92 (1992).Google Scholar
[7] Hu, Y. and Mackenzie, J. D., J. Mat. Sci., 27,4415–4420 (1992).Google Scholar
[8] Jones, S. M., Friberg, S. E., Sjoblom, J., J. Mat. Sci., 29,4075–80 (1994).Google Scholar
[9] Kokubo, T., Kushitani, H., Sakka, S., Kitsugi, T. and Yamamuro, T., J. Biomed. Mater. Res., 24, 721–734 (1990).Google Scholar
[10] Almeida, R. M., Guiton, T. A. and Pantano, C. G., J. Non-Cryst. Solids, 119, 238–241 (1990).Google Scholar
[11] Li, P., Ohtsuki, C., Kokubo, T., Nakanishi, K., Soga, N., Nakamura, T. and Yamamuro, T., J. Am. Ceram. Soc., 75, 2094–2097 (1992).Google Scholar
[12] Anderson, D. R., in Infrared. Raman and Ultraviolet Spectroscopy, edited by Smith, A. L., (JOHN WILEY & SONS, N. Y., 1974), pp. 247–286.Google Scholar