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Growth control of different Fusarium species by selected flavones and flavonoid mixtures

Published online by Cambridge University Press:  01 May 1998

ARTUR M. S. SILVA ,
MARTIN WEIDENBÖRNER  and
JOSÉ A. S. CAVALEIRO
ARTUR M. S. SILVA
Affiliation:
Department of Chemistry, University of Aveiro, 3810 Aveiro, Portugal
MARTIN WEIDENBÖRNER
Affiliation:
Institut für Angewandte Mikrobiologie Universität Giessen, Senckenbergstr. 3, 35390 Giessen, Germany
JOSÉ A. S. CAVALEIRO
Affiliation:
Department of Chemistry, University of Aveiro, 3810 Aveiro, Portugal
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Abstract

The antifungal activity of five substituted flavones and their mixtures with unsubstituted flavone or a flavanone was tested on malt extract agar against five Fusarium spp. 4′-Methylflavone and 2′,6′-dichloroflavone showed the highest activity while 4′-benzyloxyflavone caused the lowest inhibition of all test substances. A significant increase in the antifungal effect of the substituted flavones could be observed if mixtures in combination with the unsubstituted flavone or flavanone were used. Some aspects of structure–activity relationships are discussed.

Type
Research Article
Information
Mycological Research , Volume 102 , Issue 5 , May 1998 , pp. 638 - 640
Copyright
The British Mycological Society 1998

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