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Phenotypic diversity and fungal fitness

Published online by Cambridge University Press:  30 June 2005

SIMON V. AVERY
SIMON V. AVERY
Affiliation:
School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD Email. Simon.Avery@nottingham.ac.uk Tel. +44-115-9513315. Fax. +44-115-9513251
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Abstract

Individual fungal cells within genetically-uniform populations can exhibit striking phenotypic variability. This phenotypic heterogeneity has been proposed recently to promote the fitness of fungal populations, independently of fitness contributions arising from genetic diversity. Consequently, several major recent studies have been focused on unravelling the physiological and molecular bases for heterogeneity. This article provides an overview of the current state of play in this emerging field, with a focus on heterogeneity in the single-cell yeast Saccharomyces cerevisiae and on the novel methodologies being developed to study heterogeneity.

Keywords

cell individualityflow cytometrygene expressionstochasticitynoisecell cycle
Type
Original Article
Information
Mycologist , Volume 19 , Issue 2 , May 2005 , pp. 74 - 80
Copyright
© 2005 Cambridge University Press

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