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Cell contact-inhibition signaling as part of wound-healing processes in brain

Published online by Cambridge University Press:  13 November 2008

Ximena A. Lanosa  and
Jorge A. Colombo
Ximena A. Lanosa
Affiliation:
Unidad de Neurobiología Aplicada (UNA), CEMIC, Av. Galván 4102 (C1431FWO), Buenos Aires, Argentina
Jorge A. Colombo*
Affiliation:
Unidad de Neurobiología Aplicada (UNA), CEMIC, Av. Galván 4102 (C1431FWO), Buenos Aires, Argentina
*
Correspondence should be addressed to: Jorge A. Colombo, U.N.A. (CEMIC) Av. Galván 4102 (C1431FWO), Buenos Aires, Argentina, phone: 54 11 4545 6589 ext. 8712 fax: 54 11 4546 8200 email: drjacolombo@yahoo.com
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Abstract

Cell contact-dependent signaling is a major regulatory mechanism in the organization of developing tissues and in the reorganization (post-injury responses) of specialized tissues in multicellular organisms. In this review we contribute to the further understanding of post-injury recovery processes in adult nervous tissue. We emphasize evidence that supports the involvement of cell contact-inhibition signaling in the cell proliferation, growth and differentiation that occurs during healing and neural reorganization after brain damage.

Keywords

Contact signalingbrain-tissue reorganizationwound repaircell communication
Type
Research Article
Information
Neuron Glia Biology , Volume 4 , Issue 1 , February 2008 , pp. 27 - 34
Copyright
Copyright © Cambridge University Press 2008

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