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Numerical Simulation of Red Blood Cell Suspensions Behind a Moving Interface in a Capillary

Published online by Cambridge University Press:  09 August 2018

Shihai Zhao  and
Tsorng-Whay Pan
Shihai Zhao*
Affiliation:
Department of Mathematics, University of Houston, Houston, Texas 77204, USA.
Tsorng-Whay Pan*
Affiliation:
Department of Mathematics, University of Houston, Houston, Texas 77204, USA.
*
*Corresponding author.Email address:shhzhao@math.uh.edu
Email: pan@math.uh.edu
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Abstract

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC) membrane is modeled as a spring network. As by the nature of the problem, the computational domain is moving with either a designated RBC or an interface in an infinitely long two-dimensional channel with an undisturbed flow field in front of the computational domain. The tanking-treading and the inclination angle of a cell in a simple shear flow are briefly discussed for the validation purpose. We then present and discuss the results of the motion of red blood cells behind a moving interface in a capillary, which show that the RBCs with higher velocity than the interface speed form a concentrated slug behind the moving interface.

Keywords

65M6076M1076Z05Red blood cellsmoving domainimmersed boundary method
Type
Research Article
Information
Numerical Mathematics: Theory, Methods and Applications , Volume 7 , Issue 4 , November 2014 , pp. 499 - 511
Copyright
Copyright © Global Science Press Limited 2014

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