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Patients’ quality of life: Validation of the functional assessment of cancer therapy-bone marrow transplant (FACT-BMT) instrument for the Mexican population

Published online by Cambridge University Press:  04 March 2020

Liliana Rivera-Fong Open the ORCID record for Liliana Rivera-Fong [Opens in a new window] ,
Corina Benjet ,
Rebeca Robles García ,
Lara Traeger ,
José Luis Aguilar Ponce ,
Luis Manuel Valero Saldaña ,
Brenda Lizeth Acosta Maldonado ,
Silvia Rivas Vera ,
Oscar Galindo Vázquez  and
Angélica Riveros Rosas
Liliana Rivera-Fong*
Affiliation:
National University of Mexico, Mexico City, Mexico National Cancer Institute, Mexico City, Mexico
Corina Benjet
Affiliation:
Global Mental Health Research Center, Department of Epidemiological and Psychosocial Research, “Ramón de la Fuente Muñiz” National Institute of Psychiatry, Ministry of Health, Mexico City, Mexico
Rebeca Robles García
Affiliation:
Global Mental Health Research Center, Department of Epidemiological and Psychosocial Research, “Ramón de la Fuente Muñiz” National Institute of Psychiatry, Ministry of Health, Mexico City, Mexico
Lara Traeger
Affiliation:
Harvard Medical School, Boston, MA Department of Psychiatry, Massachusetts General Hospital, Boston, MA
José Luis Aguilar Ponce
Affiliation:
National Cancer Institute, Mexico City, Mexico
Luis Manuel Valero Saldaña
Affiliation:
National Cancer Institute, Mexico City, Mexico
Brenda Lizeth Acosta Maldonado
Affiliation:
National Cancer Institute, Mexico City, Mexico
Silvia Rivas Vera
Affiliation:
National Cancer Institute, Mexico City, Mexico
Oscar Galindo Vázquez
Affiliation:
National Cancer Institute, Mexico City, Mexico
Angélica Riveros Rosas
Affiliation:
National University of Mexico, Mexico City, Mexico
*
Author for correspondence: Liliana Rivera-Fong. Universidad Ave. 3004, Copilco Universidad, 04510 Mexico City, Mexico. E-mail: lmeylenf@hotmail.com
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Abstract

Objective

The functional assessment of cancer therapy-bone marrow transplant (FACT-BMT) is a widely used instrument to assess quality of life (QOL) in hematopoietic stem cell transplant (HSCT) patients, but there is little evidence of its validity in Latin American populations. This study evaluated the psychometric properties of the Spanish language version of the FACT-BMT in Mexican patients.

Method

First, the original version was piloted with 15 HSCT patients to obtain an adequate cultural version, resulting in the adaptation of one item. After that, the new version was completed by 139 HSCT patients.

Results

The results showed a FACT factor structure that explains 70.84% of the total variance, a factor structure similar to the original FACT structure, and with a high internal consistency (Cronbach's alpha = 0.867). For the BMT subscale, the best factor structure included 17 items which explain 61.65% of the total variance with an adequate internal consistency (Cronbach's alpha = 0.696).

Significance of the results

The FACT-BMT was found to be a valid and reliable instrument to evaluate QOL in Mexican patients. Our results constitute new FACT-BMT empirical evidence that supports its clinical and research uses.

Keywords

Hematopoietic stem cell transplantationMexicoNeoplasmsPsychometricsQuality of life
Type
Original Article
Information
Palliative & Supportive Care , Volume 18 , Issue 5 , October 2020 , pp. 557 - 568
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Copyright
Copyright © Cambridge University Press 2020

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