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Immunological differences in Eimeria maxima: effect of a mixed immunizing inoculum on heterologous challenge

Published online by Cambridge University Press:  06 April 2009

P. L. Long
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PW17 2DA
B. J. Millard
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PW17 2DA

Summary

The immunological differences known to exist between laboratory strains of Eimeria maxima was confirmed. Protection against challenge with different strains or field isolates of the species could be achieved by including small numbers (25 oocysts) of each in the immunizing inoculum. Similar protection was obtained when 4 distinct populations which were allowed to interbreed were used in the immunizing inoculum. This hybrid mixture of E. maxima was used to immunize chickens against challenge with 7 new isolates of E. maxima from poultry houses in different parts of England. The results show that although immunological differences exist within E. maxima good protection against many strains of this species may be achieved by initial infection with the hybrid mixture of E. maxima.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1979

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