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Strongyloides ratti in virgin female rats: studies of oestrous cycle effects and general variability

Published online by Cambridge University Press:  06 April 2009

P. A. G. Wilson ,
Maureen Cameron  and
D. S. Scott
P. A. G. Wilson
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh, EH9 3JT
Maureen Cameron*
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh, EH9 3JT
D. S. Scott
Affiliation:
University of Edinburgh, Department of Zoology, West Mains Road, Edinburgh, EH9 3JT
*
*Previously Maureen Gentle.
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Summary

There were no differences in mean intestinal worm burdens 8 days after subcutaneous injection of 4000 infective larvae of Strongyloides ratti into rats in dioestrus, pro-oestrus, oestrus and metoestrus. Thus, changes in the hormonal environment of the migrating larvae dependent on the oestrous cycle did not alter the worms' destination or affect their potential for development. In particular, the results are prima facie evidence that prolactin is not, on its own, responsible for the re-orientation of larvae in the tissues of nursing mothers. Other sources of variability in experimental S. ratti infections are analysed and the ‘exact dose’ technique offered as a corrective for some procedural errors.

Type
Research Article
Information
Parasitology , Volume 76 , Issue 2 , April 1978 , pp. 221 - 227
Copyright
Copyright © Cambridge University Press 1978

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References

REFERENCES

Barrington, E. J. W. (1963). An Introduction to General and Comparative Endocrinology. Oxford: Clarendon Press.Google Scholar
Katz, F. F. (1967). On a host sex difference in Strongyloides ratti intestinal worm burdens in rats. Proceedings of the Pennsylvania Academy of Science 41, 30–7.Google Scholar
Nagle, C. A. & Rosner, J. M. (1976). Plasma norepinephrine during the rat estrous cycle and after progesterone treatment to the ovariectomized estrogen-primed rat. Neuroendocrinology 22, 89–96.CrossRefGoogle Scholar
Saunders, A., Terry, L. C., Audet, J., Brazeau, P. & Martin, J. B. (1976). Dynamic studies of growth hormone and prolactin secretion in the female rat. Neuroendocrinology 21, 193–203.CrossRefGoogle ScholarPubMed
Short, R. V. (1972). Role of hormones in sex cycles. In Reproduction in Mammals, book 3: Hormones in Reproduction (ed. Austin, C. R. and Short, R. V.), pp. 42–72. Cambridge: Cambridge University Press.Google Scholar
Tucker, H. A. (1974). General endocrinological control of lactation. In Lactation: A Comprehensive Treatise, vol. 1 (ed. Larson, B. L. and Smith, V. R.), pp. 277–326. New York and London: Academic Press.Google Scholar
Wilson, P. A. G. (1977). The effect of the suckling stimulus on the migration of Strongyloides ratti in lactating rats. Parasitology 75, 233–9.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., Gentle, M. & Scott, D. S. (1976 a). Milk-borne infection of rats with Strongyloides ratti and Nippostrongylus brasiliensis. Parasitology 72, 355–60.CrossRefGoogle ScholarPubMed
Wilson, P. A. G., Gentle, M. & Scott, D. S. (1976 b). Dynamic determinants of the route of larval Strongyloides ratti in lactating rats and the control of experimental error hi quantitative studies of milk transmission of skin-penetrating roundworms. Parasitology 73, 399–406.CrossRefGoogle Scholar
Zamirdin, M. & Wilson, P. A. G. (1974). Strongyloides ratti: relative importance of maternal sources of infection. Parasitology 69, 445–53.CrossRefGoogle ScholarPubMed