Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-19T19:26:19.865Z Has data issue: false hasContentIssue false
  • English
  • Français

Transfer of immunity against Hymenolepis nana in mice with lymphoid cells or serum from infected donors

Published online by Cambridge University Press:  06 April 2009

C. Palmas ,
D. Wakelin  and
F. Gabriele
C. Palmas
Affiliation:
Istituto di Parassitologia, Facoltà di Medicina, Università di Cagliari, Via della Pineta 77, 09100 Cagliari, Italy
D. Wakelin
Affiliation:
Department of Zoology, University of Nottingham, University Park, Nottingham NG7 2RD
F. Gabriele
Affiliation:
Istituto di Parassitologia, Facoltà di Medicina, Università di Cagliari, Via della Pineta 77, 09100 Cagliari, Italy
Get access Rights & Permissions [Opens in a new window]

Summary

Immunity to Hymenolepis nana was adoptively transferred to recipient mice of 4 strains using mesenteric lymph node cells (MLNC), spleen cells (SC), and/or serum taken from infected donor mice. Donor cells capable of transferring immunity appeared in the mesenteric lymph nodes and spleen at an early stage (5 days) after infection. Immunity was most effectively transferred with MLNC and immune serum did not enhance this effect. It is suggested that effective immunity to H. nana involves both antibody and T cell-mediated inflammatory events.

Type
Research Article
Information
Parasitology , Volume 89 , Issue 2 , October 1984 , pp. 287 - 294
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Asano, K., Nakamura, F. & Okamoto, K. (1982). Passive protection of nude mice with lymphocytes from mice infected with Hymenolepis nana eggs. Japanese Journal of Parasitology 31, 391–400.Google Scholar
Di Conza, J. J. (1969). Protective action of passively transferred immune serum and immunoglobulin fractions against tissue invasive stages of the dwarf tapeworm. Hymenolepis nana. Experimental Parasitology 25, 368–75.CrossRefGoogle ScholarPubMed
Dineen, J. K. & Wagland, B. M. (1966). The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea pig. II. The relative susceptibility of the larvae and adult stages of the parasite to immunological attack. Immunology 11, 47–57.Google Scholar
Ferretti, G., Gabriele, F. & Palmas, C. (1980). Methodology in experimental infections of mice with Hymenolepis nana. Bollettino di Zoologia 47, 165–84.CrossRefGoogle Scholar
Friedberg, W., Neas, B. R., Faulkner, D. N. & Friedberg, M. H. (1967). Immunity to Hymenolepis nana: Transfer by spleen cells. Journal of Parasitology 53, 895–6.CrossRefGoogle ScholarPubMed
Friedberg, W., Neas, B. R., Faulkner, D. N. & Congdon, C. C. (1979). Hymenolepis nana: intestinal tissue phase in actively immunized mice. Journal of Parasitology 65, 61–4.CrossRefGoogle ScholarPubMed
Heyneman, D. (1962). Studies on helminth immunity IV. Rapid onset of resistance by the white mouse against a challenging infection with eggs of Hymenolepis nana (Cestoda: Hymenolepididae). Journal of Immunology 88, 210–20.Google ScholarPubMed
Ito, A. (1975). In vitro oncospheral agglutination given by immune sera from mice infected, and rabbits injected, with eggs of Hymenolepis nana. Parasitology 71, 465–73.CrossRefGoogle ScholarPubMed
Ito, A. (1977). The mode of passive protection against Hymenolepis nana induced by serum transfer. International Journal for Parasitology 7, 67–71.CrossRefGoogle ScholarPubMed
Isaak, D. D., Jacobson, R. H. & Reed, N. D. (1977). The course of Hymenolepis nana infections in thymus-deficient mice. International Archives of Allergy and Applied Immunology 55, 504–13.CrossRefGoogle ScholarPubMed
Larsh, J. E. (1942). Transmission from mother to offspring of immunity against the mouse cestode, Hymenolepis nana var. fraterna. American Journal of Hygiene 36, 187–94.Google Scholar
Ogilvie, B. M. & Jones, V. E. (1968). Passive protection with cells or antiserum against Nippostronglus brasiliensis in the rat. Parasitology 55, 939–49.CrossRefGoogle Scholar
Okamoto, K. (1968). Effect of neonatal thymectomy on acquired resistance to Hymenolepis nana in mice. Japanese Journal of Parasitology 17, 53–9.Google Scholar
Okamoto, K. (1970). Hymenolepis nana depression and restoration of acquired immunity in neonatally thymectomized mice. Experimental Parasitology 27, 28–32.CrossRefGoogle ScholarPubMed
Selby, G. R. & Wakelin, D. (1973). Transfer of immunity against Trichuris muris in the mouse by serum and cells. International Journal for Parasitology 3, 717–22.CrossRefGoogle ScholarPubMed
Wakelin, D. & Donachie, A. M. (1981). Genetic control of immunity to Trichinella spiralis. Donor bone marrow cells determine responses to infection in mouse radiation chimaeras. Immunology 43, 787 –92.Google ScholarPubMed
Wakelin, D., Grencis, R. K. & Donachie, A. M. (1982). Short lived, dividing cells mediate adoptive transfer of immunity to Trichinella spiralis in mice. II. In vivo characteristics of the cells. Immunology 46, 451–7.Google Scholar
Wakelin, D. & Lloyd, M. (1976). Accelerated expulsion of adult Trichinella spiralis in mice given lymphoid cells and serum from infected donors. Parasitology 72, 307–15.CrossRefGoogle ScholarPubMed
Weinmann, C. J. (1966). Immunity mechanisms in cestode infection. In Biology of Parasites (ed. Soulsby, E. J. L.), pp. 301–320. New York: Academic Press.Google Scholar
Weinmann, C. J. (1968). Effects of splenectomy and neonatal thymectomy on acquired immunity to the dwarf tapeworm, Hymenolepis nana. Experimental Parasitology 22, 68–72.CrossRefGoogle Scholar
Williams, J. F. (1979). Recent advances in the immunology of cestode infections. Journal of Parasitology 65, 337–9.CrossRefGoogle ScholarPubMed