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Duration of immunity to East Coast fever (Theileria parva infection of cattle)

Published online by Cambridge University Press:  06 April 2009

M. J. Burridge
Affiliation:
Immunological Research on Tick-borne Cattle Diseases and Tick Control Project,* East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
S. P. Morzaria
Affiliation:
Immunological Research on Tick-borne Cattle Diseases and Tick Control Project,* East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
M. P. Cunningham
Affiliation:
Immunological Research on Tick-borne Cattle Diseases and Tick Control Project,* East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
C. G. D. Brown
Affiliation:
Immunological Research on Tick-borne Cattle Diseases and Tick Control Project,* East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya

Extract

Forty-five cattle, which had recovered from EOF and been kept free from reexposure to infection for periods of 1–43 months, were given a single uniform lethal challenge using a stabilate prepared from triturated infected ticks. All withstood the challenge which killed the five controls. There was an increase in the incidence of mild febrile reactions with time since last exposure to T. parva, indicating a gradual loss of immunity in the absence of reinfection. The duration of the immunity was not related to the severity of the initial reaction.

We are indebted to our colleagues on the Immunological Research on Tickborne Cattle Diseases and Tick Control Project, with whom we designed and carried out the experiment.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1972

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