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Effect of dimetridazole on transmission of Histomonas meleagridis by Heterakis gallinarum

Published online by Cambridge University Press:  06 April 2009

M. B. Chute
Affiliation:
U.S. Department of Agriculture, Animal Parasitology Institute, Science and Education Administration, Beltsville, Maryland 20705
Anne M. Chute
Affiliation:
U.S. Department of Agriculture, Animal Parasitology Institute, Science and Education Administration, Beltsville, Maryland 20705
G. C. Wilkins
Affiliation:
U.S. Department of Agriculture, Animal Parasitology Institute, Science and Education Administration, Beltsville, Maryland 20705

Summary

The administration of an antihistomonal drug, dimetridazole, at a dose of 0·08% in feed, controlled experimental infections with Histomonas meleagridis in chickens. The treated birds developed no lesions and the duration of infection with H. meleagridis was reduced. This drug regimen, however, did not always prevent incorporation of H. meleagridis into eggs of Heterakis gallinarum; heterakid eggs pooled from medicated chickens in which H. meleagridis had never been detected transmitted the protozoan to 1 of 10 turkeys fed the eggs. Thus, therapeutic treatment of chickens with dimetridazole may reduce, but not eliminate, transmission of H. meleagridis by eggs of H. gallinarum from medicated birds.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1978

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References

REFERENCES

Chute, A. M., Lund, E. E. & Wilkins, G. C. (1976). Comparative responses of White Leghorn and New Hampshire chickens to experimental infections with Histomonas meleagridis and Heterakis gallinarum. Poultry Science 55, 710–13.CrossRefGoogle Scholar
Condren, H. B., Davies, R. E., Deyoe, C. W., Zavala, M. A., Creger, C. R. & Couch, J. R.(1963). Studies on the effect of 1,2-dimethyl-5-nitroimidazole on growth and reproduction in turkeys and its residual concentration in tissues. Poultry Science 42, 585.CrossRefGoogle Scholar
Gardiner, J. L. & Wehr, E. E. (1950). Selecting experimental groups of chicks by weight. Proceedings of the Helminthological Society of Washington 17, 25–6.Google Scholar
Lee, D. L. (1971). Helminths as vectors of micro-organisms. In Ecology and Physiology of Parasites: A Symposium (ed. Fallis, A. M.), pp. 104–22. University of Toronto Press.CrossRefGoogle Scholar
Lucas, J. M. S. (1962). Dimetridazole. II. Therapeutic activity and toxicity in the treatment of experimental histomoniasis in turkeys. Veterinary Record 74, 759–62.Google Scholar
Lucas, J. M. S. (1963). Dimetridazole. III. The permanent suppression of experimental histomoniasis in turkeys following treatment. Veterinary Record 75, 695–6.Google Scholar
Lund, E. E. & Burtner, R. H. Jr (1957). Infectivity of Heterakis gallinae eggs with Histomonas meleagridis. Experimental Parasitology 6, 189–93.CrossRefGoogle ScholarPubMed
Lund, E. E. & Chute, A. M. (1972 a). Transfer of ten-day Heterakis gallinarum larvae: effect on retention and development of the heterakids, and liberation of Histomonas and Parahistomonas. Experimental Parasitology 31, 361–9.CrossRefGoogle ScholarPubMed
Lund, E. E. & Chute, A. M. (1972 b). Potential of young and mature guinea fowl in contaminating soil with Histomonas-bearing heterakid eggs. Avian Diseases 16, 1079–86.CrossRefGoogle Scholar
Lund, E. E. & Chute, A. M. (1973 a). Two consecutive transfers of Heterakis gallinarum: effects on cecal worms and on histomonads. Journal of Helminthology 47, 141–53.CrossRefGoogle ScholarPubMed
Lund, E. E. & Chute, A. M. (1973 b). Means of acquisition of Histomonas meleagridis by eggs of Heterakis gallinarum. Parasitology 66, 335–42.CrossRefGoogle ScholarPubMed
Lund, E. E. & Chute, A. M. (1974). The reproductive potential of Heterakis gallinarum in various species of galliform birds: implications for survival of H. gallinarum and Histomonas meleagridis to recent tunes. International Journal for Parasitology 4, 455–61.CrossRefGoogle Scholar
Shelton, G. C. & Mcdougle, H. C. (1970). Observations concerning the use of 1-methyl-2-carbamoyloxymethyl-5-nitroimidazole against experimentally induced histomoniasis in turkey poults. Poultry Science 49, 1077–81.CrossRefGoogle ScholarPubMed
Wehr, E. E., Farr, M. W. & Moloughlin, D. K. (1958). Chemotherapy of blackhead in turkeys. Journal of the American Veterinary Medical Association 132, 439–45.Google Scholar