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Further Experiments on the Action of Emetine in Cultures of Entamoeba histolytica

Published online by Cambridge University Press:  06 April 2009

P. P. Laidlaw ,
Clifford Dobell  and
Ann Bishop
P. P. Laidlaw
Affiliation:
National Institute for Medical Research, London, N.W.3.
Clifford Dobell
Affiliation:
National Institute for Medical Research, London, N.W.3.
Ann Bishop
Affiliation:
National Institute for Medical Research, London, N.W.3.
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Extract

In 1926 two of us published the results of a long series of experiments on the toxic action of the alkaloids of ipecacuanha in cultures of several species of entozoic amoebae. These experiments led us to definite conclusions regarding the differential susceptibility of the various species of amoebae studied, and the relative potency of several alkaloids employed. They also showed clearly that the full specific action of emetine, on susceptible amoebae, is only disclosed if the alkaloid is allowed to act for a sufficient time (two or three days.)

Type
Research Article
Information
Parasitology , Volume 20 , Issue 2 , July 1928 , pp. 207 - 220
Copyright
Copyright © Cambridge University Press 1928

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