Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-16T13:56:39.406Z Has data issue: false hasContentIssue false
  • English
  • Français

Immunity to coccidiosis: protective effect of transferred serum in Eimeria maxima infections

Published online by Cambridge University Press:  06 April 2009

M. Elaine Rose
M. Elaine Rose
Affiliation:
Houghton Poultry Research Station, Houghton, Huntingdon
Get access Rights & Permissions [Opens in a new window]

Extract

Serum taken between 2 and 3 weeks after infection of the donors with E. maxima conferred a considerable degree of protection against infection with the homologous organism when injected daily into young recipients. Different pools of such sera had differing activities, but the majority gave protection of 50% or more whereas a few were inactive.

The degree of protection obtained was dose-dependent, varying directly with the volume of serum injected and inversely with the size of the challenge oocyst inoculum.

A course of injections started early in the life-cycle had a greater effect than those started in mid- or late cycle even when comparatively large volumes of serum were given.

Protection was species specific; serum obtained from birds infected with E. maxima did not protect against E. praecox or E. acervulina.

The assistance of Mrs Patricia Hesketh is gratefully acknowledged, as is the help of other members of the staff of the Parasitology Department. Mr P. Townsend, Senior Poultry Attendant, supervised the cleaning and sterilization of cages and the collection of faecal samples.

Type
Research Article
Information
Parasitology , Volume 62 , Issue 1 , February 1971 , pp. 11 - 25
Copyright
Copyright © Cambridge University Press 1971

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Augustin, R. & Ridges, A. P. (1963). Immunity mechanisms in Eimeria meleagrimitis. In Immunity to Protozoa, pp. 296–335. Garnham, P. C. C., Pierce, A. E. & Roitt, I. (editors). Blackwell Scientific Publications.Google Scholar
Bachman, G. W. (1930). Serological studies in coccidiosis of rabbits. American Journal of Hygiene 12, 624–40.Google Scholar
Becker, E. R. (1935). The mechanism of murine coccidiosis. American Journal of Hygiene 21, 389–401.Google Scholar
Becker, E. R. & Hall, P. R. (1933). Quantitative character of coccidian infection in recipients of blood from immunised animals. Proceedings of the Society for Experimental Biology and Medicine 30, 789–90.CrossRefGoogle Scholar
Becker, E. R., Hall, P. R. & Hager, A. (1932). Quantitative biometric and host-parasite studies on Eimeria miyarii and Eimeria separata in rats. Iowa State College Journal of Science 6, 299–316.Google Scholar
Fitzgerald, P. R. (1964). Attempted immunization of young calves against Eimeria bovis. Journal of Protozoology 11, 46–51.CrossRefGoogle ScholarPubMed
Gilden, R. V. & Rosenquist, G. L. (1963). Duration of antibody response to soluble antigen:incorporation of sulphur-35 methionine into normal and antibody globulin. Nature, London 200, 1116–17.CrossRefGoogle ScholarPubMed
Gray, D. F. & Cheers, C. (1969). The sequence of enhanced cellular activity and protective humoral factors in murine pertussis immunity. Immunology 17, 889–96.Google ScholarPubMed
Horton-Smith, C., Beattie, J. & Long, P. L. (1961). Resistance to Eimeria tenella and its transference from one caecum to the other in individual fowls. Immunology 4, 111–21.Google Scholar
Horton-Smith, C. & Long, P. L. (1959). The effects of different anti-coccidial agents on the intestinal coccidioses of the fowl. Journal of Comparative Pathology and Therapeutics 69, 192–207.CrossRefGoogle Scholar
Horton-Smith, C., Long, P. L. & Pierce, A. E. (1963). Behaviour of invasive stages of Eimeria tenella in the immune fowl (Gallus domesticus). Experimental Parasitology 14, 66–74.CrossRefGoogle ScholarPubMed
Huang, K-Y., Schultz, W. W. & Gordon, F. B. (1968). Interferon induced by Plasmodium berghei. Science 162, 123–4.CrossRefGoogle ScholarPubMed
Iványi, J., Hraba, T. & Černý, J. (1964). The elimination of heterologous and homologous serum proteins in chickens at various ages. Folia biologica, Praha 10, 275–83.Google ScholarPubMed
Jahiel, R. I., Vilcek, J., Nussenzweig, R. & Vanderberg, J. (1968). Interferon inducers protect mice against Plasmodium berghei malaria. Science 161, 802–4.CrossRefGoogle ScholarPubMed
Kaliss, N. (1958). Immunological enhancement of tumor homografts in mice: a review. Cancer Research 18, 992–1003.Google ScholarPubMed
Leathem, W. D. & Burns, W. C. (1967). Effects of the immune chicken on the endogenous stages of Eimeria tenella. Journal of Parasitology 51, 180–5.CrossRefGoogle Scholar
Long, P. L. & Milne, B. S. (1971). The effect of an interferon inducer on Eimeria maxima in the chicken. Parasitology (in Press.)CrossRefGoogle ScholarPubMed
Long, P. L. & Rose, M. E. (1962). Attempted transfer of resistance to Eimeria tenella infections from domestic hens to their progeny. Experimental Parasitology 12, 75–81.Google ScholarPubMed
Long, P. L. & Rowell, J. G. (1958). Counting oocysts of chicken coccidia. Laboratory Practice 7, 515–18, 534.Google Scholar
Mackaness, G. B. & Blanden, R. V. (1967). Cellular immunity. Progress in Allergy 11, 89–140.Google ScholarPubMed
Patterson, R., Youngner, J. S., Weigle, W. O. & Dixon, F. J. (1962). The metabolism of serum proteins in the hen and chick and secretion of serum proteins by the ovary of the hen. Journal of General Physiology 45, 501–13.CrossRefGoogle Scholar
Pierce, A. E., Long, P. L. & Horton-Smith, C. (1962). Immunity to Eimeria tenella in young fowls (Gallus domesticus). Immunology 5, 129–52.Google ScholarPubMed
Pierce, A. E., Long, P. L. & Horton-Smith, C. (1963). Attempts to induce a passive immunity to Eimeria tenella in young fowls (Gallus domesticus). Immunology 6, 37–47.Google ScholarPubMed
Rose, M. E. & Long, P. L. (1962). Immunity to four species of Eimeria in the fowl. Immunology 5, 79–92.Google Scholar
Rose, M. E. (1963). Some aspects of immunity to Eimeria infections. Annals of the New York Academy of Sciences 113, 383–9.CrossRefGoogle ScholarPubMed
Schulz, W. W., Huang, K-Y. & Gordon, F. B. (1968). Role of interferon in experimental mouse malaria. Nature, London 220, 709–10.CrossRefGoogle Scholar
Tyzzer, E. E. (1929). Coccidiosis in gallinaceous birds. American Journal of Hygiene 10, 269–383.Google Scholar