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Q fever (Coxiella burnetii) reservoir in wild brown rat (Rattus norvegicus) populations in the UK

Published online by Cambridge University Press:  06 April 2009

J. P. Webster ,
G. Lloyd  and
D. W. Macdonald
J. P. Webster
Affiliation:
Wildlife Conservation Research Unit, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS
G. Lloyd
Affiliation:
Centre for Applied Microbiology and Research, Division of Pathology, Porton Down, Salisbury, Wiltshire SP4 0JG
D. W. Macdonald
Affiliation:
Wildlife Conservation Research Unit, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS
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Extract

Seroprevalence of Coxiella burnetii, the causal agent of Q fever in humans, was examined in wild brown rat populations from 4 Oxfordshire farmsteads (n = 127), 9 Somerset homesteads (n = 98), and 1 captive enclosure (n = 88) in the UK. Seroprevalence ranged between 7 and 53%, the lowest being within the captive population and the highest on dairy farmsteads with sheep present. This is the first reported investigation of C. burnetii in wild rats outside India. We suggest that the high Seroprevalence among rats (i) provides evidence that wild rats constitute an important reservoir for C. burnetii in the UK, and (ii) explains why cats, as frequent predators of rats, are so important in the epidemiology of this disease.

Keywords

Q feverCoxiella burnetiiwild ratscatsaerosol transmission
Type
Research Article
Information
Parasitology , Volume 110 , Issue 1 , January 1995 , pp. 31 - 35
Copyright
Copyright © Cambridge University Press 1995

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References

REFERENCES

Aitken, I. D. (1989). Clinical aspects and the prevention of Q-fever in animals. European Journal of Epidemiology 5, 420–4.CrossRefGoogle ScholarPubMed
Ayres, J., Blair, I., Burge, P. S. & The Communicable Disease Surveillance Centre (1989). A large Q-fever outbreak in the West Midlands: a preliminary note. Communicable Diseases Report 35, 3–4.Google Scholar
Babudieri, B. (1959). Q-fever: a zoonosis. Advances in Veterinary Science 5, 81–154.Google Scholar
Baldelli, R., Cimmino, C. & Pasquinelli, M. (1992). Dog-transmitted zoonoses: a serological survey in the province of Bologna. Annali del Istituto Superiore di Sanita (Roma) 28, 493–46.Google ScholarPubMed
Berdoy, M. (1994). Making decisions in the wild: constraints, conflicts and communication in foraging wild rats. In Behavioural Aspects of Feeding (ed. Galef, B. G. Jr., Mainardi, M. & Valsechi, P.), pp. 289–313. London: Harwood Academic Publishers. Ettore Majorana International Life Science Series.Google Scholar
Bishop, J. A. & Hartley, D. J. (1976). The size and age structure of rural populations of Rattus norvegicus containing individuals resistant to the anticoagulant poison warfarin. Journal of Animal Ecology 45, 623–6.CrossRefGoogle Scholar
Calhoun, J. B. (1962). The ecology and sociology of the Norway rat. US Department of Health, Education and Welfare, P. H.S. No. 1008. Bethesda, Maryland.Google Scholar
Field, P. R., Hunt, J. G. & Murphy, A. M. (1983). Detection and persistence of specific IgM antibody to Coxiella burnetti by Enzyme-Linked Immunosorbent Assay: A comparison with Immunofluorescence and Complement Fixation Tests. Journal of Infectious Diseases 148, 477–81.Google Scholar
Geddes, A. (1983). Q-fever. British Medical Journal 287, 927–8.Google Scholar
Grist, N. R. (1959). The persistence of Q-fever infection in a dairy herd. Veterinary Record 71, 839.Google Scholar
Hosier, D. W. & Durning, J. P. (1975). Involvement of sex hormones in the resistance of ICR mice to Nematospiroides dubius. Journal of Parasitology 63, 564–6.CrossRefGoogle Scholar
Lang, G. H. (1990). Coxiellosis (Q fever) in animals. In Q-fever: The Disease, Vol 1 (ed. Marrie, T. J.), pp. 23–48. Boca Raton: CRC Press.Google Scholar
Leyhausen, P. (1979). Cat Behaviour: The Predatory and Social Behaviour of Domestic and Wild Cats. New York, London: Garland Series in Ethology, Garland S.T.P.M. Press.Google Scholar
MacDonald, D. W., Apps, P. J., Carr, G. M. & Kerby, G. (1987). Social dynamics, nursing coalitions and infanticide among farm cats, Felis catus. Advances in Ethology 28, 5–65.Google Scholar
Marrie, T. J. (1990 a). Q-fever–A review. Canadian Veterinary Journal 3, 555–64.Google Scholar
Marrie, T. J. (1990 b). Epidemiology of Q fever. In Q- fever: The Disease, Vol. 1, (ed. Marrie, T. J.), pp. 49–70. Boca Raton: CRC Press.Google Scholar
Marrie, T. J., Van Buren, J. & Fraser, J. (1985). Seroepidemiology of Q-fever among domestic animals in Nova Scotia. American Journal of Public Health 75, 763–6.Google Scholar
Meehan, A. P. (1984). Rats and Mice: their Biology and Control. The Rentokil Library, Rentokil Ltd, Kent: Brown Knight & Truscott Ltd.Google Scholar
Osterman, J. V. & Eisemann, C. S. (1980). Rickettsia. In Manual of Clinical Immunology, 2nd Edn. (ed. Rose, N. R. & Friedman, H.), pp. 707–713. Washington D.C.: American Society for Microbiology.Google Scholar
Peter, O., Dupuis, G., Peacock, M. G. & Burgdofer, W. (1987). Comparison of Enzyme-Linked Immunosorbent Assay and Complement Fixation and Indirect Fluorescent-Antibody tests for detection of Coxiella burnetti antibody. Journal of Clinical Microbiology 25, 1063–7.Google Scholar
Peter, O., Dupuis, G., Bee, D., Luthy, R., Nicolet, J. & Burgdofer, W. (1988). Enzyme-Linked Immunosorbent Assay for the diagnosis of chronic Q-fever. Journal of Clinical Microbiology 26, 1978–82.CrossRefGoogle ScholarPubMed
Tylewska-Wierbanowska, S. K. & Kruszewka, D. (1990). Q-fever sexually transmitted infection ? Journal of Infectious Diseases 161, 368–9.Google Scholar
Yadav, M. P., Rarotra, J. R. & Sethi, M. S. (1979). The occurrence of coxiellosis among rodents and shrews in the Taraie area of Utta Pradesh. Journal of Wildlife Diseases 15, 11–14.Google Scholar