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Reinfection with hookworm after chemotherapy in Papua New Guinea

Published online by Cambridge University Press:  06 April 2009

R. J. Quinnell ,
A. F. G. Slater ,
P. Tighe ,
E. A. Walsh ,
A. E. Keymer  and
D. I. Pritchard
R. J. Quinnell
Affiliation:
Department of Zoology, South Parks Road, Oxford OX1 3PS
A. F. G. Slater
Affiliation:
Department of Zoology, South Parks Road, Oxford OX1 3PS
P. Tighe
Affiliation:
Department of Life Science, Nottingham University, Nottingham NG7 2RD
E. A. Walsh
Affiliation:
Department of Life Science, Nottingham University, Nottingham NG7 2RD
A. E. Keymer
Affiliation:
Department of Zoology, South Parks Road, Oxford OX1 3PS
D. I. Pritchard
Affiliation:
Department of Life Science, Nottingham University, Nottingham NG7 2RD
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Summary

Reinfection with hookworm (Necator americanus) following chemotherapy was studied over 2 years in a rural village in Madang Province, Papua New Guinea. The prevalence of hookworm infection had returned to pre-treatment levels after 2 years, and the geometric mean hookworm burden had returned to 58 % of the pre-treatment value. The rate of acquisition of adult worms was independent of host age, and was estimated as a geometric mean of 2·9–3·3 worms/host/year (arithmetic mean 7·9–8·9 worms/host/year). There was significant predisposition to hookworm infection; the strength of this predisposition did not vary significantly between age or sex classes.

Keywords

hookwormNecator americanusreinfectionpredispositionchemotherapyPapua New Guinea
Type
Research Article
Information
Parasitology , Volume 106 , Issue 4 , May 1993 , pp. 379 - 385
Copyright
Copyright © Cambridge University Press 1993

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