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The release of antigens by Plasmodium falciparum

Published online by Cambridge University Press:  06 April 2009

R. J. M. Wilson  and
R. K. Bartholomew
R. J. M. Wilson
Affiliation:
National Institute for Medical Research, Mill Hill, London NW7 1AA, and MRC Laboratories, Fajara, The Gambia, West Africa
R. K. Bartholomew
Affiliation:
National Institute for Medical Research, Mill Hill, London NW7 1AA, and MRC Laboratories, Fajara, The Gambia, West Africa
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Extract

Antigens were released in vitro from human red cells infected with Plasmodium falciparum only when parasites reached a late stage of schizogony (probably at rupture of infected red cells during reinvasion). Immune complexes formed if antibody was present. Serum from immune Aotus monkeys opsonized parasite debris from artificially disrupted infected Aotus red cells.

Type
Research Article
Information
Parasitology , Volume 71 , Issue 2 , October 1975 , pp. 183 - 192
Copyright
Copyright © Cambridge University Press 1975

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