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A study upon passive immunity in experimental trichiniasis

Published online by Cambridge University Press:  06 April 2009

James T. Culbertson  and
Samuel S. Kaplan
James T. Culbertson
Affiliation:
From the Department of Bacteriology, College of Physicians and Surgeons, Columbia University, New York
Samuel S. Kaplan
Affiliation:
From the Department of Bacteriology, College of Physicians and Surgeons, Columbia University, New York
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Extract

Protection against infection with Trichinella spiralis is conferred upon mice by the passive transfer to them of a specific immune serum from rabbits. A smaller percentage of mice treated with the immune serum die, and fewer larvae invade the muscles of the treated mice than among control animals. The action of the antibody of the immune serum appears to be directed specifically against the ingested larvae which are maturing to adult worms in the intestine of the infected animals. The results obtained thus far indicate that an immune serum would have little therapeutic value in the later stages of the disease.

Type
Research Article
Information
Parasitology , Volume 30 , Issue 2 , June 1938 , pp. 156 - 166
Copyright
Copyright © Cambridge University Press 1938

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References

REFERENCES

Bachman, G. W. (1929). A precipitin test in experimental trichiniasis. Second report. J. Prev. Med., Lond., 3, 465.Google Scholar
Bachman, G. W. & Oliver Gonzalez, J. (1935). Immunization in rats against Trichinella spiralis. Proc. Soc. exp. Biol., N.Y., 35, 215.CrossRefGoogle Scholar
Ducas, H. (1921). L'immunité dans la Trichinose. Thése, pp. 47. Paris, Jouve et Cie.Google Scholar
Hall, M. C. & Wigdor, M. (1918). An experimental study of serum therapy in trichinosis. Arch. intern. Med. 22, 601.CrossRefGoogle Scholar
McCoy, O. R. (1931). Immunity of rats to reinfection with Trichinella spiralis. Amer. J. Hyg. 14, 484.Google Scholar
Salzer, B. F. (1916). A study of an epidemic of 14 cases of trichinosis with cures by serum therapy. J. Amer. med. Ass. 67, 579.CrossRefGoogle Scholar
Salzer, B. F. (1917). A study of an epidemic of trichinosis with special reference to serum therapy. Med. Rec., N.Y., 91, 261.Google Scholar
Sarles, M. P. & Taliaferro, W. H. (1936). The local points of defence and the passive transfer of acquired immunity to Nippostrongylus muris in rats. J. infect. Dis. 59, 207.Google Scholar
Schwartz, B. (1917). Serum therapy for trichinosis. J. Amer. med. Ass. 69, 884.Google Scholar
Spink, W. W. (1934). The effects of vaccines, bacterial and parasitical infections on eosinophilia in trichinous animals. Arch. intern. Med. 54, 805.Google Scholar
Spink, W. W. & Augustine, D. L. (1935). The diagnosis of trichiniasis, with special reference to skin and precipitin tests. J. Amer. med. Ass. 104, 1801.CrossRefGoogle Scholar
Trawinski, A. (1935). Studien über Immunität bei Trichinose. Zbl. Bakt. 134, 145.Google Scholar