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Vaccination of lambs against infection with Taenia ovis using antigens collected during short-term in vitro incubation of activated T. ovis oncospheres

Published online by Cambridge University Press:  06 April 2009

M. D. Rickard  and
A. J. Adolph
M. D. Rickard
Affiliation:
Department of Paraclinical Sciences, University of Melbourne, Veterinary Clinical Centre, Princes Highway, Werribee, Victoria 3030, Australia
A. J. Adolph
Affiliation:
Department of Paraclinical Sciences, University of Melbourne, Veterinary Clinical Centre, Princes Highway, Werribee, Victoria 3030, Australia
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Extract

Activated oncospheres of Taenia ovis were incubated for 24 h or 48 h at 37.5°C in Medium 858 alone or in Medium 858 enriched with 20% lamb serum or foetal calf serum. Antigens contained in the supernatant medium from these incubations were concentrated, emulsified in Freund's incomplete adjuvant and injected intramuscularly into lambs. These lambs developed a very high level of immunity to subsequent challenge infection with T. ovis eggs.

Type
Research Article
Information
Parasitology , Volume 75 , Issue 2 , October 1977 , pp. 183 - 188
Copyright
Copyright © Cambridge University Press 1977

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