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Zoonotic pathogens in fluctuating common vole (Microtus arvalis) populations: occurrence and dynamics

Published online by Cambridge University Press:  24 September 2018

Ruth Rodríguez-Pastor Open the ORCID record for Ruth Rodríguez-Pastor [Opens in a new window] ,
Raquel Escudero ,
Xavier Lambin Open the ORCID record for Xavier Lambin [Opens in a new window] ,
Mª Dolors Vidal ,
Horacio Gil ,
Isabel Jado ,
Manuela Rodríguez-Vargas ,
Juan José Luque-Larena  and
François Mougeot Open the ORCID record for François Mougeot [Opens in a new window]
Ruth Rodríguez-Pastor*
Affiliation:
Dpto. Ciencias Agroforestales, ETSIIAA, Universidad de Valladolid, Avda. de Madrid 44, 34004, Palencia, Spain Instituto Universitario de Investigación en Gestión Forestal Sostenible, Palencia, Spain
Raquel Escudero
Affiliation:
Laboratorio de Referencia e Investigación en Patógenos Especiales. Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220, Majadahonda, Madrid, Spain
Xavier Lambin
Affiliation:
School of Biological Sciences, University of Aberdeen, Aberdeen, UK
Mª Dolors Vidal
Affiliation:
Área de Microbiología, Facultad de Medicina, Universidad de Castilla-La Mancha, 13071, Ciudad Real, Spain
Horacio Gil
Affiliation:
Laboratorio de Referencia e Investigación en Patógenos Especiales. Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220, Majadahonda, Madrid, Spain
Isabel Jado
Affiliation:
Laboratorio de Referencia e Investigación en Patógenos Especiales. Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220, Majadahonda, Madrid, Spain
Manuela Rodríguez-Vargas
Affiliation:
Laboratorio de Referencia e Investigación en Patógenos Especiales. Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220, Majadahonda, Madrid, Spain
Juan José Luque-Larena
Affiliation:
Dpto. Ciencias Agroforestales, ETSIIAA, Universidad de Valladolid, Avda. de Madrid 44, 34004, Palencia, Spain Instituto Universitario de Investigación en Gestión Forestal Sostenible, Palencia, Spain
François Mougeot
Affiliation:
Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC-UCLM-JCCM), Ronda de Toledo s/n, 13071, Ciudad Real, Spain
*
Author for correspondence: Ruth Rodríguez-Pastor, E-mail: ruth.rodriguez@uva.es
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Abstract

Diseases and host dynamics are linked, but their associations may vary in strength, be time-lagged, and depend on environmental influences. Where a vector is involved in disease transmission, its dynamics are an additional influence, and we often lack a general understanding on how diseases, hosts and vectors interact. We report on the occurrence of six zoonotic arthropod-borne pathogens (Anaplasma, Bartonella, Borrelia, Coxiella, Francisella and Rickettsia) in common voles (Microtus arvalis) throughout a population fluctuation and how their prevalence varies according to host density, seasonality and vector prevalence. We detected Francisella tularensis and four species of Bartonella, but not Anaplasma, Borrelia, Coxiella or Rickettsia. Bartonella taylorii and B. grahamii prevalence increased and decreased with current host (vole and mice) density, respectively, and increased with flea prevalence. Bartonella doshiae prevalence decreased with mice density. These three Bartonella species were also more prevalent during winter. Bartonella rochalimae prevalence varied with current and previous vole density (delayed-density dependence), but not with season. Coinfection with F. tularensis and Bartonella occurred as expected from the respective prevalence of each disease in voles. Our results highlight that simultaneously considering pathogen, vector and host dynamics provide a better understanding of the epidemiological dynamics of zoonoses in farmland rodents.

Keywords

BartonellafleasFrancisella tularensisrodent- and arthropod-borne pathogensMicrotus arvalismixed infectionspopulation outbreakszoonotic diseases dynamics
Type
Research Article
Information
Parasitology , Volume 146 , Issue 3 , March 2019 , pp. 389 - 398
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Copyright
Copyright © Cambridge University Press 2018 

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Footnotes

*

These authors contributed equally.

†

Equal supervision.

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