According to Hugh Mellor in Real Time II (1998, Ch. 12), assuming the logical independence of causal facts and the ‘law of large numbers’, causal loops are impossible because if they were possible they would produce inconsistent sets of frequencies. I clarify the argument, and argue that it would be preferable to abandon the relevant independence assumption in the case of causal loops.

John Maynard Smith has defended against philosophical criticism the view that developmental biology is the study of the expression of information encoded in the genes by natural selection. However, like other naturalistic concepts of information, this “teleosemantic” concept is equally applicable to many non-genetic factors in development. Maynard Smith also fails to show that developmental biology is concerned with teleosemantic information. Some other ways to support Maynard Smith's conclusion are considered. It is argued that on any definition of information the view that development is the expression of genetic information is misleading. Some reasons for the popularity of that view are suggested.

The existence of “undermining futures” appears to show that a contradiction can be deduced from the conjunction of Humean supervenience (HS) about chance and the Principal Principle. A number of strategies for rescuing HS from this problem have been proposed recently. In this paper, a novel way of defending HS from the threat is presented, and it is argued that this defense has advantages not shared by others. In particular, it requires no revisionism about chance, and it is equally available to defenders of HS who hold HS to be necessary and those who hold it to be contingent.

The Principle of Indifference, which dictates that we ought to assign two outcomes equal probability in the absence of known reasons to do otherwise, is vulnerable to well-known objections. Nevertheless, the appeal of the principle, and of symmetry-based assignments of equal probability, persists. We show that, relative to a given class of symmetries satisfying certain properties, we are justified in calling certain outcomes equally probable, and more generally, in defining what we call relative probabilities. Relative probabilities are useful in providing a generalized approach to conditionalization. The technique is illustrated by application to simple examples.

A Bayesian account of independent evidential support is outlined. This account is partly inspired by the work of C. S. Peirce. I show that a large class of quantitative Bayesian measures of confirmation satisfy some basic desiderata suggested by Peirce for adequate accounts of independent evidence. I argue that, by considering further natural constraints on a probabilistic account of independent evidence, all but a very small class of Bayesian measures of confirmation can be ruled out. In closing, another application of my account to the problem of evidential diversity is also discussed.

Two Bayesian approaches to choosing between statistical models are contrasted. One of these is an approach which Bayesian statisticians regularly use for motivating the use of AIC, BIC, and other similar model selection criteria, and the other one is a new approach which has recently been proposed by Bandyopadhayay, Boik, and Basu. The latter approach is criticized, and the basic ideas of the former approach are presented in a way that makes them accessible to a philosophical audience. It is also pointed out that the former approach establishes a new, philosophically interesting connection between the notions of simplicity and informativeness.

Critics of Bayesianism often assert that scientists are not Bayesians. The widespread use of Bayesian statistics in the field of radiocarbon calibration is discussed in relation to this charge. This case study illustrates the willingness of scientists to use Bayesian statistics when the approach offers some advantage, while continuing to use orthodox methods in other contexts. The case of radiocarbon calibration, therefore, suggests a picture of statistical practice in science as eclectic and pragmatic rather than rigidly adhering to any one theoretical position.