Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-26T20:44:00.223Z Has data issue: false hasContentIssue false
  • English
  • Français

Characterization of medicinal Senna genetic resources

Published online by Cambridge University Press:  15 April 2009

J. B. Morris
J. B. Morris*
Affiliation:
Plant Genetic Resources Conservation Unit, USDA, ARS, 1109 Experiment Street, Griffin, GA 30223, USA
*
*Corresponding author. E-mail: brad.morris@ars.usda.gov
Get access Rights & Permissions [Opens in a new window]

Abstract

At 50% maturity, regenerating Senna species were characterized for morphological traits, seed reproduction, and evaluated for regeneration. Quality plants regenerated from all accessions produced 1018 to more than 21,215 total seeds. Principal component analysis revealed which traits contributed the greatest to variability among coffee senna accessions. Senna species have potential to produce pharmaceutical products and can be grown as medicinal plants. The flavonoids quercetin and kaempferol found in Senna species have been clinically shown to have anti-pancreatic cancer properties.

Keywords

genetic resourcespharmaceuticalsphytochemicalsprincipal component analysisSenna
Type
Research Article
Information
Plant Genetic Resources , Volume 7 , Issue 3 , December 2009 , pp. 257 - 259
Copyright
Copyright © NIAB 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chomnawang, MT, Surassmo, S, Nukoolkarn, VS and Gritsanapan, W (2005) Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria. Journal of Ethnopharmacology 101: 330–333.CrossRefGoogle ScholarPubMed
ILDIS (1994) Plants and their constituents. In: Bisby, FA et al. (eds) Phytochemical Dictionary of the Leguminosae. New York: Chapman & Hall, pp. 1–748.Google Scholar
Martin, DE, Blum, R, Doto, J, Galbraith, H and Ballow, C (2007) Multiple-dose pharmacokinetics and safety of bevirimat, a novel inhibitor of HIV maturation, in healthy volunteers. Clinical Pharmacokinetics 46: 589–598.CrossRefGoogle ScholarPubMed
National Plant Germplasm System (2008) Germplasm Resources Information Network (GRIN). Database Management Unit (DBMU), National Plant Germplasm System. US Department of Agriculture, Beltsville, MD.Google Scholar
Nothlings, U, Murphy, SP, Wilkens, LR, Henderson, BE and Kolonel, LN (2007) Flavonols and pancreatic cancer risk: the multiethnic cohort study. American Journal of Epidemiology 166: 924–931.CrossRefGoogle ScholarPubMed
Qian, K, Nakagawa-Goto, K, Yu, D, Morris-Natschke, SL, Nitz, TJ, Kilgore, N, Allaway, GP and Lee, KH (2007) Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives. Bioorganic and Medicinal Chemistry Letters 17: 6553–6557.CrossRefGoogle ScholarPubMed
Smith, PF, Ogundele, A, Forrest, A, Wilton, J, Salzwedel, K, Doto, J, Allaway, GP and Martin, DE (2007) Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3′,3′-dimethylsuccinyl) betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrobial Agents and Chemotherapy 51: 3574–3581.CrossRefGoogle Scholar