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Powder diffraction data and preliminary spectroscopic and thermal characterization of pinaverium bromide, a drug used for functional gastrointestinal disorders

Published online by Cambridge University Press:  14 January 2021

José H. Quintana Mendoza Open the ORCID record for José H. Quintana Mendoza [Opens in a new window] ,
Andrea P. Aparicio  and
J. A. Henao
José H. Quintana Mendoza*
Affiliation:
Grupo de Investigación Biocalorimetría, Departamento de Química, Facultad de Ciencias Básicas, Universidad de Pamplona, Km 1, vía Bucaramanga, Pamplona, Colombia
Andrea P. Aparicio
Affiliation:
Grupo de Investigación en Química Estructural (GIQUE), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia
J. A. Henao
Affiliation:
Grupo de Investigación en Química Estructural (GIQUE), Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia
*
a)Author to whom correspondence should be addressed. Electronic mail: jhquintanam@gmail.com
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Abstract

Pinaverium bromide (C26H41Br2NO4) is an active pharmaceutical ingredient (API) usually prescribed for the relief of spasm and functional gastrointestinal disorders. This work reports its powder diffraction data, Raman and FT-IR spectroscopy and thermal characterization. Indexing of the powder diffraction pattern showed this material crystallizes in a monoclinic unit cell with a = 16.00(4) Å, b = 8.901(2) Å, c = 19.225(4) Å, β = 98.68(3)°, and V = 2808.2(6) Å3.

Keywords

pinaverium bromidepowder diffraction datagastrointestinal spasm
Type
New Diffraction Data
Information
Powder Diffraction , Volume 36 , Issue 1 , March 2021 , pp. 20 - 24
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Copyright
Copyright © International Centre for Diffraction Data 2021

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