Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-27T10:28:43.579Z Has data issue: false hasContentIssue false

Evaluation of Intravenous Tramadol for Use in the Prehospital Situation by Ambulance Paramedics

Published online by Cambridge University Press:  28 June 2012

Michael E. Ward*
Affiliation:
Consultant Anaesthetist, Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford, England
John Radburn
Affiliation:
Senior Training Officer, Oxfordshire Ambulance NHS Trust, Churchill Drive, Headington, Oxford, England
Steve Morant
Affiliation:
Manager, Biometric Division, Searle, High Wycombe, Buckinghamshire, England
*
Consultant Anaesthetist, Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford OX3 9DU, England

Abstract

Introduction:

An evaluation of the opioid analgesic tramadol (Zydol, Searle United Kingdom) was carried-out by ambulance paramedics to assess its efficacy in providing pain relief in the prehospital situation.

Methods:

Type of subjects—Patients suffering severe pain from any cause uncontrolled by other simple methods.

Number of subjects—101 patients received tramadol and 41 patients served as a control. Study design—Random, open study.

Statistical tests—Pain score at scene and on arrival at hospital were compared using Fisher's exact tests (2 sides). Logistic regression analyses also were applied to other factors.

Results:

Pain scores improved for 93.1% of the tramadol treated patients and for 44.0% of the controls. A total of 30.7% of patients treated with tramadol complained of nausea after treatment compared with 17.1% before treatment and with 12.2% of the control patients.

Conclusion:

Pain was significantly decreased by the administration of tramadol. It was safe with only minimal side effects, the major one being nausea. Suggestions are made for areas of further study.

Type
Original Research
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. United Kingdom Ambulance Service Basic Training Manual Section 6.9. 1996 Published by National Health Service Training Directorate, BristolGoogle Scholar
2. Chambers, JA, Guly, HR: Prehospital intravenous nalbuphine administered by paramedics. Resuscitation 1994;27:153158.CrossRefGoogle ScholarPubMed
3. Simpson, HK, Smith, GB: A survey of paramedic skills in the United Kingdom and Channel Islands. BMJ 1996;313:10521053.CrossRefGoogle ScholarPubMed
4. Focus on tramadol. Adis Drug Reprint. 1993;46;2:311340.Google Scholar
5. Vickers, MD, O'Flaherty, D, Szekely, SM, Read, M, Yoshizumi, J: Tramadol: Pain relief by an opiod without respiratory depression. Anaesthesia 1992;47:291296.CrossRefGoogle Scholar
6. Houmes, R-JM, Voets, MA, Verkaaik, A, Erdmann, W, Lachmann, B: Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression. Anesthesia and Analgesia 1992;74:510514.CrossRefGoogle ScholarPubMed
7. Vickers, MD, Paravicini, D. Comparison of tramadol with morphine for postoperative analgesia following abdominal surgery. Europ J Anaesthesiology 1989;12:17.Google Scholar
8. Viegas, OAC, Khaw, B, Ratnam, SS: Tramadol in labour pain in primiparous patients: A prospective comparative clinical trial. European Journal Obstetrics Gynaecology and Reproductive Biology 1993;49:131135.CrossRefGoogle ScholarPubMed
9. Wallenstein, SL, Hondle, RW: The clinical evaluation of analgesic effectiveness. In: Ehrenpris, S., Neidle, A (Eds). Methods in Narcotic Research. New York: Marcel Dekker, 1975, pp 127145.Google Scholar
10. Ward, ME, Fenn, C, McGowan, A: A randomised double blind placebo controlled multicentre study to compare intravenous tramadol with intravenous nalbuphine in patients with moderate to severe pain, attended by ambulance paramedics. Study in progress.Google Scholar