Decoys ‘R’ Us: A database of incorrect conformations to improve protein structure prediction

RAM SAMUDRALA; MICHAEL LEVITT

doi:10.1110/ps.9.7.1399

Abstract

The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the function on a set of computer-generated conformations (decoys) to determine whether it can readily distinguish native-like conformations from nonnative ones. We have created “Decoys ‘R’ Us,” a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved.

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Decoys ‘R’ Us: A database of incorrect conformations to improve protein structure prediction

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