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Carbamazepine monitoring

Published online by Cambridge University Press:  02 January 2018

Carol Paton  and
Andrew W. Procter
Carol Paton
Affiliation:
Bexley Hospital, Bexley, Kent DA5 2BW
Andrew W. Procter
Affiliation:
Bexley Hospital, Bexley, Kent DA5 2BW
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Background of the study

Rationale for monitoring carbamazepine levels

Carbamazepine fulfils some of the criteria required in order to render a drug suitable for serum level monitoring in that there is poor inter-individual reproducibility of the serum levels achieved with fixed dosage regimes, interbrand differences in bioavailability are known to occur and serum levels can be raised significantly by several commonly prescribed drugs; dextropropoxyphene (a constituent of coprozamol), erythromycin, isoniazid and cimetidine.

Type
Audit
Information
Psychiatric Bulletin , Volume 17 , Issue 12 , December 1993 , pp. 718 - 720
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Royal College of Psychiatrists 1993

References

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