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Thyroid dysfunction in adults with Down's syndrome

Published online by Cambridge University Press:  02 January 2018

Tharayil Suresh  and
Pauline Robertson
Tharayil Suresh
Affiliation:
Royal Scottish National Hospital, Larbert, Stirlingshire FK5 6EH
Pauline Robertson
Affiliation:
Royal Scottish National Hospital, Larbert, Stirlingshire FK5 6EH
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Thyroid treatment was used at the beginning of the 20th century for people with Down's syndrome, and an improvement in the physical and mental response was noted (Smith & Berg, 1976). Later studies reported conflicting findings about the prevalence and type of thyroid dysfunction (Sare et al, 1978; Lobo et al, 1980) but there now seems little doubt about the existence of a high prevalence of hypothyroidism (Mani, 1988; Dinani & Carpenter, 1990).

Type
Audit
Information
Psychiatric Bulletin , Volume 17 , Issue 8 , August 1993 , pp. 477 - 478
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Royal College of Psychiatrists 1993

References

Dinani, S. & Carpenter, S. (1990) Down's syndrome and thyroid disorder. Journal of Mental Deficiency Research, 34, 187–193.Google Scholar
Lobo, E. de H., Khan, M. & Tew, J. (1980) Community study of hypothyroidism in Down's syndrome. British Medical Journal, i, 1253.CrossRefGoogle Scholar
Mani, C. (1988) Hypothyroidism in Down's syndrome. British Journal of Psychiatry, 153, 102–104.Google Scholar
Sare, Z., Ruvalcaba, R. H. A. & Kelley, V. C. (1978) Prevalence of thyroid disorder in Down's syndrome. Clinical Genetics, 14, 154–158.CrossRefGoogle Scholar
Smith, G. F. & Berg, J. M. (1976) Down's Anomaly. London: Churchill Livingstone.Google Scholar
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