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Daily variations of the urine content of 3-methoxy-4-hydroxyphenylglycol in two manic-depressive patients

Published online by Cambridge University Press:  09 July 2009

P. A. Bond ,
F. A. Jenner  and
Gwyneth A. Sampson
P. A. Bond
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, Sheffield
F. A. Jenner
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, Sheffield
Gwyneth A. Sampson
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, Sheffield
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Synopsis

Daily measurements of MHPG in urine have been carried out in two patients with manic-depressive psychosis. In both cases, levels in mania were elevated and in depression lowered with interval levels which were intermediate and within the normal range. The results lend some support to the suggestion that there might be an increase in brain noradrenaline metabolism in mania and a decrease in depression.

Type
Preliminary Communication
Information
Psychological Medicine , Volume 2 , Issue 1 , February 1972 , pp. 81 - 85
Copyright
Copyright © Cambridge University Press 1972

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References

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