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Dynamic mutations and psychiatric genetics1

Published online by Cambridge University Press:  09 July 2009

Michael C. O'Donovan  and
Michael J. Owen
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Abstract

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Type
Editorial
Information
Psychological Medicine , Volume 26 , Issue 1 , January 1996 , pp. 1 - 6
Copyright
Copyright © Cambridge University Press 1996

References

REFERENCES

Asherson, P., Walsh, C., Williams, J., Sargeant, M., Taylor, C., Clements, A., Gill, M., Owen, M. & McGuffin, P. (1994). Imprinting and anticipation – are they relevant to genetic studies of schizophrenia? British Journal of Psychiatry 164, 619–624.CrossRefGoogle ScholarPubMed
Bassett, A. S. & Honer, W. G. (1994). Evidence for anticipation in schizophrenia. American Journal of Human Genetics 54, 864–870.Google ScholarPubMed
Brook, J. D., McCurrach, M. E., Harley, H. G., Buckler, A. J., Church, D., Aburatani, H., Hunter, K., Stanton, V. P., Thirion, J. P., Hudson, T., Sohn, R., Zemelman, B., Snell, R. G., Rundle, S. A., Crow, S., Davies, J., Shelbourne, P., Buxton, J., Jones, C., Juvonen, V., Johnson, K., Harper, P. S., Shaw, D. J. & Housman, D. E. (1992). Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell 68, 799–808.CrossRefGoogle ScholarPubMed
Duyao, M., Ambrose, C., Myers, R., Novelletto, A., Persichetti, F., Frontali, M., Folstein, S., Ross, C., Franz, M., Abbott, M., Gray, J., Conneally, P., Young, A., Penney, J., Hollingsworth, Z., Shoulson, I., Lazzarini, A., Falek, A., Koroshetz, W., Sax, D., Bird, E., Vonsattel, J., Bonilla, E., Alvir, J., Bickham Conde, J., Cha, J. H., Dure, L., Gomez, F., Ramos, M., Sanchez-Ramos, J., Snodgrass, S., de Young, M., Wexler, N., Moscowitz, C., Penchaszadeh, G., MacFarlane, H., Anderson, M., Jenkins, B., Srinidhi, J., Barnes, G., Gusella, J. & MacDonald, M. (1993). Trinucleotide repeat length instability and age of onset in Huntington's disease. Nature Genetics 4, 387–392.CrossRefGoogle ScholarPubMed
Flint, J. (1992). Implications of genomic imprinting for psychiatric genetics. Psychological Medicine 22, 5–10.CrossRefGoogle ScholarPubMed
Fu, Y. H., Kuhl, D. P. A., Pizzuti, A., Pieretti, M., Sutcliffe, J. S., Richards, S., Verkerk, A. J. M. H., Holden, J. J. A., Fenwick, R. G. Jr., Warren, S. T., Oostra, B. A., Nelson, D. L. & Caskey, C. T. (1991). Variation of the CGG repeat at the Fragile-X site results in genetic instability: resolution of the Sherman paradox. Cell 67, 1047–1058.CrossRefGoogle ScholarPubMed
Gyapay, G., Morissette, J., Vignal, A., Dib, C., Fizames, C., Millasseau, P., Marc, S., Bernardi, G., Lathrop, M. & Weissenbach, J. (1994). The 1993–94 Genethon human genetic linkage map. Nature Genetics 7, 246–249.CrossRefGoogle ScholarPubMed
Harley, H. G., Rundle, S. A., MacMillan, J. C., Myring, J., Brook, J. D., Crow, S., Reardon, W., Fenton, I., Shaw, D. J. & Harper, P. S. (1993). Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy. American Journal of Human Genetics 52, 1164–1174.Google ScholarPubMed
Harper, P. S. (1989). Myotonic Dystrophy. W. B. Saunders Co.: London.Google ScholarPubMed
Huntington's Disease Collaborative Research Group (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's Disease chromosomes. Cell 72, 971–983.CrossRefGoogle Scholar
Kawaguchi, Y., Okamoto, T., Taniwaki, M., Aizawa, M., Inoue, M., Katayama, S., Kawakami, H., Nakamura, S., Nishimura, M., Akiguchi, I., Kimura, J., Narumiya, S. & Kakizuka, A. (1994). CAG expansions in a novel gene for Machado–Joseph disease at chromosome 14q32.1. Nature Genetics 8, 221–228.CrossRefGoogle Scholar
Knight, S. J., Flannery, A. V., Hirst, M. C., Campbell, L., Christodoulou, Z., Phelps, S. R., Pointon, J., Middleton-Price, H. R., Barnicoat, A., Pembrey, M. E., Holland, J., Oostra, B. A., Bobrow, M. & Davies, K. E. (1993). Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation. Cell 74, 127–134.CrossRefGoogle ScholarPubMed
La Spada, A. R., Wilson, E. M., Lubahn, D. B., Harding, A. E. & Fischbeck, K. H. (1991). Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352, 77–79.CrossRefGoogle ScholarPubMed
Lindblad, K., Nylander, P. O., De Bruyn, A., Sourey, D., Zander, C., Engstrom, C., Holmgren, G., Hudson, T., Chotai, J., Mendlewicz, J., Broeckhoven, C. V., Schalling, M. & Adolfsson, R. (1995). Detection of expanded CAG repeats in bipolar affective disorder using the repeat expansion detection (RED) method. Neurobiology of Disease 2, 55–62.CrossRefGoogle ScholarPubMed
Little, B. W., Brown, P. W., Rodgers-Johnson, P., Perl, D. P. & Gajdusek, D. C. (1986). Familial myoclonic dementia masquerading as Creutzfeldt–Jakob disease. Annals of Neurology 20, 231–239.CrossRefGoogle ScholarPubMed
McGuffin, P., Asherson, P., Owen, M. & Farmer, A. (1994). The strength of the genetic effect – is there an environmental influence in the aetiology of schizophrenia? British Journal of Psychiatry 164, 593–599.CrossRefGoogle ScholarPubMed
McInnis, M. G., McMahon, F. J., Chase, G. A., Simpson, S. G., Ross, C. A. & DePaulo, J. R. Jr. (1993). Anticipation in bipolar affective disorder. American Journal of Human Genetics 53, 385–930.Google ScholarPubMed
Morel, B. A. (1857). Traite des degenerescences. J. B. Bailliere: Paris.Google Scholar
Mott, F. W. (1910). Hereditary aspect of nervous and mental diseases. British Medical Journal ii, 1013–1020.CrossRefGoogle Scholar
Nagafuchi, S., Yanagisawa, H., Ohsaki, E., Shirayama, T., Tadokoro, K., Inoue, T. & Yamada, M. (1994). Structure and expression of the gene responsible for the triplet repeat disorder, dentatorubral and pallidoluysian atrophy (DRPLA). Nature Genetics 8, 177–182.CrossRefGoogle ScholarPubMed
Nylander, P. O., Engstrom, C., Chotai, J., Wahlstrom, J. & Adolfsson, R. (1994). Anticipation in Swedish families with bipolar affective disorder. Journal of Medical Genetics 31, 686–689.CrossRefGoogle ScholarPubMed
O'Donovan, M. C., Guy, C., Craddock, N., Murphy, K. C., Cardno, A. G., Jones, L. A., Owen, M. J. & McGuffin, P. (1995). Expanded CAG repeats in schizophrenia and bipolar disorder. Nature Genetics 10, 380–382.CrossRefGoogle ScholarPubMed
Orr, H. T., Chung, M. Y., Banfi, S., Kwiatkowski, T. J. Jr., Servadio, A., Beaudet, A. L., McCall, A. E., Duvick, L. A., Ranum, L. P. & Zoghbi, H. Y. (1993). Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nature Genetics, 4(3), 221–226.CrossRefGoogle ScholarPubMed
Owen, M. & McGuffin, P. (1992). The molecular genetics of schizophrenia. British Medical Journal 305, 664–665.CrossRefGoogle ScholarPubMed
Penrose, L. S. (1945). Survey of cases of familial mental illness. Published in 1991 in European Archives of Clinical Neuroscience 240, 314–324.Google Scholar
Penrose, L. S. (1948). The problem of anticipation in pedigrees of dystrophia myotonica. Annals of Eugenics 14, 125–132.CrossRefGoogle ScholarPubMed
Pieretti, M., Zhang, F. P., Fu, Y. H., Warren, S. T., Oostra, B. A., Caskey, C. T. & Nelson, D. L. (1991). Absence of expression of the FMR-1 gene in Fragile-X syndrome. Cell 66, 817–822.CrossRefGoogle ScholarPubMed
Ridley, R. M., Frith, C. D., Crow, T. J. & Conneally, P. M. (1988). Anticipation in Huntington's disease is inherited through the male line but may originate in the female. Journal of Medical Genetics 25, 589–595.CrossRefGoogle ScholarPubMed
Ross, C. A., McInnis, M. G., Margolis, R. L. & Li, S. H. (1993). Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. TINS 16, 254–260.Google ScholarPubMed
Schalling, M., Hudson, T. J., Buetow, K. H. & Housman, D. E. (1992). Direct detection of novel expanded trinucleotide repeats in the human genome. Nature Genetics 4, 135–139.CrossRefGoogle Scholar
Sherman, S. L., Jacobs, P. A., Morton, N. E., Froster-Iskenius, U., Howard-Peebles, P. N., Nielsen, K. B., Partington, M. W., Sutherland, G. R., Turner, G. & Watson, M. (1985). Further segregation analysis of the fragile X syndrome with special reference to transmitting males. Human Genetics 69, 289–299.CrossRefGoogle ScholarPubMed
Snell, R. G., MacMillan, J. C., Cheadle, J. P., Fenton, I., Lazarou, L. P., Davies, P., MacDonald, M. E., Gusella, J. F., Harper, P. S. & Shaw, D. J. (1993). Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nature Genetics 4, 393–397.CrossRefGoogle ScholarPubMed
Yu, S., Pritchard, M., Kremer, E., Lynch, M., Nancarrow, J., Baker, E., Holman, K., Mulley, J. C., Warren, S. T., Schlessinger, D., Sutherland, G. R. & Richards, R. I. (1991). Fragile-X genotype characterized by an unstable region of DNA. Science 252, 1179–1181.CrossRefGoogle ScholarPubMed
Yu, S., Mulley, J., Loesch, D., Turner, G., Donnelly, A., Gedeon, A., Hillen, D., Kremer, E., Lynch, M., Pritchard, M., Sutherland, G. R. & Richards, R. I. (1992). Fragile-X Syndrome: unique genetics of the heritable unstable element. American Journal of Human Genetics 50, 968–980.Google ScholarPubMed
Willems, P. J. (1994). Dynamic mutations hit double figures. Nature Genetics 8, 213–215.CrossRefGoogle ScholarPubMed