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The possible relationship of herpes simplex virus infection to cause of retardation in severe mental handicap

Published online by Cambridge University Press:  09 July 2009

A. H. Reid ,
K. W. Martin ,
B. R. Ballinger  and
B. B. Heather
A. H. Reid*
Affiliation:
Dundee Psychiatric Service, Strathmartine Hospital, by Dundee, Departments of Bacteriology and Psychiatry, Ninewells Hospital and Medical School, Dundee
K. W. Martin
Affiliation:
Dundee Psychiatric Service, Strathmartine Hospital, by Dundee, Departments of Bacteriology and Psychiatry, Ninewells Hospital and Medical School, Dundee
B. R. Ballinger
Affiliation:
Dundee Psychiatric Service, Strathmartine Hospital, by Dundee, Departments of Bacteriology and Psychiatry, Ninewells Hospital and Medical School, Dundee
B. B. Heather
Affiliation:
Dundee Psychiatric Service, Strathmartine Hospital, by Dundee, Departments of Bacteriology and Psychiatry, Ninewells Hospital and Medical School, Dundee
*
1Address for correspondence: Dr A. H. Reid. Strathmartine Hospital, by Dundee DD3 OPG
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Synopsis

The relationship between herpes simplex virus type 1 and mental retardation is explored by studying the antibody levels to this virus in a group of 86 severely and profoundly retarded adults. A tendency towards higher antibody levels is found in patients whose retardation is of unknown aetiology. The relationship of these observations to previous research findings and the possible significance of herpes simplex virus in the aetiology of mental retardation are discussed

Type
Research Article
Information
Psychological Medicine , Volume 10 , Issue 3 , August 1980 , pp. 555 - 557
Copyright
Copyright © Cambridge University Press 1980

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References

Hierons, R., Janota, I. & Corsellis, J. A. N. (1978). The late effects of necrotizing encephalitis of the temporal lobes and limbic areas: a clinico-pathological study of 10 cases. Psychological Medicine 8, 21–42.CrossRefGoogle Scholar
Kurtz, J. B. & Sykes, D. W. (1974). Herpes simplex virus (type I) transmitted to a neonate. Lancet ii, 1580–1581.CrossRefGoogle Scholar
Lancet (1979). Leading article: Unclassified mental retardation; i, 250–251.Google Scholar
Linnemann, C. C., Buchman, T. G., Light, I. J., Ballard, J. L. & Roizman, B. (1978). Transmission of herpes simplex virus type 1 in a nursery for the new born. Identification of viral isolates by D.N.A. ‘fingerprinting’. Lancet i, 964–966.CrossRefGoogle Scholar
Nahmias, A. J., Alford, C. A. & Korones, S. B. (1970). InfectiOn of the newborn with herpes virus hominis.Advances in Paediatrics 17, 185–226.CrossRefGoogle Scholar
Smith, I. W., Peutherer, J. F. & MacCallum, F. O. (1967). The incidence of herpes virus hominis antibody in the population. Journal of Hygiene 65, 395–408.CrossRefGoogle ScholarPubMed
South, M. A., Tompkins, W. A. F., Morris, C. R. & Rawls, W. E. (1969). Congenital malformation of the central nervous system associated with genital type (type 2) herpes virus. Journal of Paediatrics 75, 13–18.CrossRefGoogle Scholar
Stadler, H., Oxman, M. N. & Herrmann, K. L. (1975). Herpes simplex virus microneutralization: a simplification of the test. Journal of Infectious Diseases 131, 423–430.Google Scholar
Tobin, J. O'H. (1975).Herpes virus hominis infection in pregnancy. Proceedings of the Royal Society of Medicine 68, 371–374.CrossRefGoogle ScholarPubMed