Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-27T11:25:45.887Z Has data issue: false hasContentIssue false
  • English
  • Français

Experimental modification of P50 suppression

Published online by Cambridge University Press:  30 April 2001

CINDY M. YEE  and
PATRICIA M. WHITE
CINDY M. YEE
Affiliation:
University of California, Los Angeles, USA
PATRICIA M. WHITE
Affiliation:
University of California, Los Angeles, USA
Get access

Abstract

White and Yee (1997) found that normal suppression of the P50 component of the event-related potential was disrupted during a paired-click paradigm when nonpsychiatric subjects performed mental arithmetic (MA) problems aloud, concurrently with the presentation of auditory stimuli. In fact, the degree of disruption reflected in the P50 suppression ratio fell within the range that is typically observed in schizophrenia patients. The present study was conducted to clarify the processes that might underlie the apparent disruption of P50 suppression during performance of an oral MA task. Participants completed a series of tasks designed to examine the impact of competing cognitive activity, competing auditory stimulation, muscle activity, and acute psychological stress on P50 amplitude and P50 suppression. Results suggested that psychological stress and heightened facial muscle activity may exert modulatory effects on P50 suppression.

Keywords

P50Sensory gatingPsychological stressorMental arithmetic taskSchizophrenia
Type
Research Article
Information
Psychophysiology , Volume 38 , Issue 3 , May 2001 , pp. 531 - 539
Copyright
2001 Society for Psychophysiological Research

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)