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Factors associated with low serum retinol levels in children aged 6–24 months in a rural South African community

Published online by Cambridge University Press:  02 January 2007

Mieke Faber  and
AJ Spinnler Benadé
Mieke Faber*
Affiliation:
National Research Programme for Nutritional Intervention, Medical Research Council, PO Box 19070, Tygerberg 7505, South Africa
AJ Spinnler Benadé
Affiliation:
National Research Programme for Nutritional Intervention, Medical Research Council, PO Box 19070, Tygerberg 7505, South Africa
*
*Corresponding author: Email mieke.faber@mrc.ac.za
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Abstract

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Objective

To identify risk factors for variation in serum retinol levels in children younger than 2 years of age in a rural South African community.

Design

Children (n=97), 6–24 months of age, were divided into two groups according to their serum retinol levels, using 20 μg dl−1 as the cut-off point. The chi-square test, Fischer exact two-tailed test and analysis of variance were used to identify related variables which were significantly different between the two groups. To evaluate simultaneously the association between several potential risk factors and low serum retinol levels, a multiple regression model for categorical data was developed which included potential risk factors that were statistically significant in the bivariate analysis as the independent variables, and either low or normal vitamin A status as the dependent variable.

Results

There was an association between serum retinol levels and: (i) the place of birth (hospital vs. home deliveries); (ii) the attitude of the care-giver towards family life; and (iii) the health status of the child. Although not included in the multiple variable model because of small numbers, all children who had a previous episode of measles, all underweight children, and all children of widowed care-givers were in the low serum retinol group.

Conclusions

The care-giver's attitude towards family life was positively associated with the child's vitamin A status, while home deliveries were associated with a low vitamin A status.

Keywords

RuralUnder 2sVitamin ARisk factors
Type
Research Article
Information
Public Health Nutrition , Volume 3 , Issue 4 , December 2000 , pp. 395 - 402
Copyright
Copyright © CABI Publishing 2000

References

1South African Vitamin A Consultative Group (SAVACG). Anthropometric, vitamin A, iron and immunisation coverage status in children aged 6–71 months in South Africa, 1994. S. Afr. Med. J. 1996; 86: 354–7.Google Scholar
2West, KP Jr, Sommer, A. Delivery of Oral Doses of Vitamin A to Prevent Vitamin A Deficiency and Nutritional Deficiency: a State-of-the-Art Review. United Nations ACC/SCN Nutrition Policy Discussion Paper No. 2. Rome: Food and Agricultural Organization, 1987.Google Scholar
3Van Stuijvenberg, ME, Kvalsvig, JD, Faber, M, Kruger, M, Kenoyer, DG, Benadé, AJS. Effect of iron-, iodine-, and β-carotene-fortified biscuits on the micronutrient status of primary school children: a randomized controlled trial. Am. J. Clin. Nutr. 1999; 69: 497–503.CrossRefGoogle ScholarPubMed
4UNICEF. Strategy for Improved Nutrition of Children and Women in Developing Countries. UNICEF: New York, 1990.Google Scholar
5Nestel, P, Herrera, MG, El Amin, A, Fawzi, W, Mohammed, KA, Weld, L.Risk factors associated with xerophthalmia in northern Sudan. J. Nutr. 1993; 123: 2115–21.Google ScholarPubMed
6Hussain, A, Kvale, G.Environmental conditions, health behavior, and mortality in siblings as risk indicators of night blindness. Am. J. Trop. Med. Hyg. 1996; 54: 309–12.CrossRefGoogle ScholarPubMed
7Ahmed, F, Khan, MR, Faruque, O, Taj, S, Hyderi, T, Jackson, AA. Serum retinol is influenced by social factors and antioxidant nutrients among adolescent girls in urban Bangladesh. Int. J. Food Sci. Nutr. 1998; 49: 39–44.CrossRefGoogle Scholar
8Rosen, DS, Sloan, NL, del Rosario, A, de la Paz, TC. Risk factors for vitamin A deficiency in rural areas of the Philippines. J. Trop. Pediatr. 1994; 40: 82–7.CrossRefGoogle ScholarPubMed
9Faber, M, Benadé, AJS. Nutritional status and dietary practices of 4–24-month-old children from a rural South African community. Public Health Nutr. 1999; 2: 179–85.CrossRefGoogle ScholarPubMed
10Faber, M, Oelofse, A, Benadé, AJS. A model for a community-based growth monitoring system. Afr. J. Health Sci. 1998; 5: 72–8.Google Scholar
11Catignani, GL, Bieri, JG. Simultaneous determination of retinol and α-tocopherol in serum or plasma by liquid chromatography. Clin. Chem. 1983; 29: 708–12.CrossRefGoogle ScholarPubMed
12Jelliffe, DB, Jelliffe, EFP. Anthropometry: major measurements. In: Jelliffe, DB, Jelliffe, EFP, eds. Community Nutritional Assessment, 1st edn. Oxford: Oxford University Press, 1989; 68–104.Google Scholar
13Gross, R, Kielman, A, Korte, R, Schoeneberger, H, Schultink, W. Guidelines for Nutrition Baseline Surveys in Communities, Version 1.2. Thailand: TW System (Thailand) Co., Ltd, 1997.Google Scholar
14Hamill, PVV, Drizd, TA, Johnson, CL, Reed, RB, Roche, AF, Moore, WM. Physical growth: National Center for Health Statistics percentiles. Am. J. Clin. Nutr. 1979; 32: 607–29.CrossRefGoogle ScholarPubMed
15Campbell, CC. Food insecurity: a national outcome or a predictor variable? J. Nutr. 1991; 121: 408–15.CrossRefGoogle ScholarPubMed
16Range, SKK, Naved, R, Bhattarai, S. Child Care Practices Associated with Positive and Negative Nutritional Outcomes for Children in Bangladesh: a Descriptive Analysis. FCND Discussion Paper No. 24. Washington, DC: Food Composition and Nutrition Division, 1997.Google Scholar
17Zeitlin, MF. Child Care and Nutrition: the Findings from Positive Deviance Research. Medford, MA: Tufts University, School of Nutrition, 1994.Google Scholar
18Faber, M, Oelofse, A, Kriek, AJ, Benadé, AJS. Breastfeeding and complementary feeding practices in a low socio-economic urban and a low socio-economic rural area. S. Afr. J. Food Sci. Nutr. 1997; 9: 43–51.Google Scholar
19Lloyd, CB, Gage-Brandon, AJ. Women's role in maintaining household: family welfare and sexual inequality in Ghana. Popul. Stud. 1993; 47: 115–31.CrossRefGoogle Scholar
20Hussain, A, Kvåle, G.Serum vitamin A in relation to socio-economic, demographic and dietary characteristics in Bangladeshi children. Acta Paediatr. 1996; 85: 971–6.CrossRefGoogle ScholarPubMed
21Faber, M, Smuts, CM, Benadé, AJS. Dietary intake of primary school children in relation to food production in a rural area in KwaZulu-Natal. Int. J. Food Sci. Nutr. 1999; 50: 57–64.CrossRefGoogle Scholar